Radiotherapy-induced nausea, vomiting associated with worsening quality of life

the ONA take:

Patients’ subjective experiences of radiotherapy-induced nausea and vomiting (RINV) correlated to the worsening of quality of life outcomes, according to a new study published online ahead of print in the journal Supportive Care in Cancer.

For the study, researchers enrolled 58 patients with gastrointestinal cancer undergoing treatment with abdominal radiotherapy alone or with concomitant chemoradiotherapy.

The investigators recorded all episodes of nausea, vomiting, and antiemetic use daily for the treatment period and the week following completion of treatment.

Results showed that in total, 351 episodes of nausea severity, duration, onset time, and 154 outcomes of vomiting onset times and contents were recorded. The most common durations of nausea were 30 minutes or less and consistent nausea all day and night.

Researchers found that longer nausea duration, greater nausea severities, the location of nausea experienced, and the onset timing and number of vomiting episodes significantly negatively impacted quality of life.

The findings suggest that the identification and amelioration of these RINV experiences could improve quality of life in patients with gastrointestinal cancer receiving radiotherapy.

Radiotherapy-induced nausea, vomiting associated with worsening quality of life
Patients’ subjective experiences of radiotherapy-induced nausea and vomiting (RINV) correlated to the worsening of quality of life outcomes.
Forty-eight patients treated with abdominal radiotherapy alone or with concomitant chemoradiotherapy were followed in a prospective study. All episodes of nausea, vomiting, and antiemetic use were recorded daily for the treatment period and the week following completion of therapy. QOL was assessed weekly using the Functional Living Index-Emesis QOL Tool (FLIE) and the EORTC QLQ-C30 core questionnaire (C30).
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