Testosterone Therapy Does Not Increase Aggressive Prostate Cancer Risk

the ONA take:

Use of testosterone therapy has increased in the last decade and the potential long-term risks associated with this therapy have been of concern.

Longitudinal studies have not found any increased risk of high-grade prostate cancer linked to this therapy, but no studies have examined the long-range implications. Results of a new study indicate that exposure to testosterone therapy over a 5-year period was not linked to increased prostate cancer risk.

Researchers based at The University of Texas Medical Branch (UTMB) at Galveston, led by Jacques Baillargeon, UTMB professor of epidemiology in the department of preventive medicine and community health, used SEER-Medicare linked data to review 52,579 men whose prostate cancer was diagnosed between January 2001 through December 2006. Five hundred seventy four men had a history of testosterone use in the 5 years previous to their cancer diagnosis.

The year of diagnosis for the respondents was found to have a similar distribution regardless of whether the men used testosterone or not.

Study results also indicate that the total number of testosterone injections also appears to have no bearing on increased prostate cancer risk. The data utilized diagnosis codes included in hospitalization, outpatient, and physician claims.

The results of this study were published in the Journal of Urology.

Study shows testosterone therapy does not increase aggressive prostate cancer risk
Use of testosterone therapy has increased in the last decade and the potential long-term risks associated with this therapy have been of concern.
A new population-based study from The University of Texas Medical Branch at Galveston showed for the first time that exposure to testosterone therapy over a five-year period was not associated with an increased risk of aggressive prostate cancer. Further, risk of high-grade prostate cancer did not increase according to the total number of testosterone injections.
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