Progesterone could be added to brain cancer therapies

the ONA take:

Study results published in the Journal of Steroid Biochemistry and Molecular Biology indicate that the hormone progesterone could play a potential role in fighting the most aggressive form of brain cancer. Researchers explored the role of progesterone as therapy for traumatic brain injury and stroke, and they discovered that progesterone, in higher does, can kill glioblastoma tumor cells and at the same time remain nontoxic toward the patient's non-cancerous cells. In other studies, progesterone has demonstrated beneficial effects in Breast and ovarian cancers, inhibited the growth of neuroblastoma cells. Standard targeted therapies have not proved effective in combatting glioblastoma, despite their success with other cancer types.


The researchers feel that more studies are needed, but that eventually human trials combining progesterone with standard therapeutic agents may be on the horizon.

Progesterone could be added to brain cancer therapies
Progesterone could be added to brain cancer therapies
The hormone progesterone could become part of therapy against the most aggressive form of brain cancer. High concentrations of progesterone kill glioblastoma cells and inhibit tumor growth when the tumors are implanted in mice, researchers have found. The findings with glioblastoma came out of Emory researchers' work on progesterone as therapy for traumatic brain injury and more recently, stroke.
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