Obtaining 16 cores is better than obtaining 12 cores for prostate cancer detection

the ONA take:

A research team from Japan found that 16-core biopsy has a slightly higher detection rate than 12-core biopsy. The researchers obtained prostate biopsies from 332 men with prostate-specific antigen (PSA) levels ranging from 4.0 to 20.0 ng/mL. All the patients underwent transrectal ultrasound-guided needle biopsy. The number of biopsy cores taken reflected local protocols. Men in the 16-core group were significantly younger and had higher PSA levels than the men in the 12-core group. Prostate cancer was detected in 33.8% of men in the 12-core group and in 44.5% of those in the 16-core group. However, 16-core biopsy found more cancer than 12-core biopsy in two subgroups of men. Anatomical distribution of detected cancers did not differ; neither did the pathological tumor grade or proportion of cancers that were deemed to be clinically insignificant. Periprocedural risks and complications were similar in the two groups of men.

Obtaining 16 cores is better than obtaining 12 cores for prostate cancer detection
Obtaining 16 cores is better than obtaining 12 cores for prostate cancer detection
Sixteen-core prostate biopsy has a slightly higher cancer detection rate than 12-core biopsy, but with a similar safety profile and no increased detection of clinically insignificant tumours, study findings show. The research was undertaken by Yasuhide Miyoshi (Yokohama City University, Japan) and team and included 332 men with prostate-specific antigen (PSA) levels in the range 4.0 to 20.0 ng/mL.
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