Stronger anticoagulation therapy may be needed for patients with metastatic cancer after bone lesion surgery

the ONA take:

A high risk for venous thromboembolism (VTE) following surgery for long-bone reconstruction was found in patients with metastatic cancer.

These findings from a study by Sidney Kimmel Medical College at Thomas Jefferson University researchers were published in Journal of Bone and Joint Surgery.

The researchers retrospectively reviewed 336 cases in which patients underwent intramedullary nailing for metastatic bone lesions.

Results demonstrated that VTEs developed in 24 patients (7.1%) in the 90 days after surgery, but they also found a low incidence of postoperative wound complications (3.1%).

In addition, 66% of the patients who had developed blood clots also had a primary cancer of the lung. Additional findings were that patients who did not receive radiotherapy after surgery had a slightly lower risk of developing a blood clot.

The researchers conclude that these findings suggest anticoagulation agent, as well as duration of therapy, should be individualized to each patient and their primary cancer. Anticoagulation therapy should also be managed with a team approach that includes the oncologic, medical, radiation, and surgical teams.

Stronger anticoagulation therapy may be needed for patients with metastatic cancer after bone lesion surgery
A high risk for venous thromboembolism following surgery for long-bone reconstruction was found in patients with metastatic cancer.
Jefferson researchers identified a high risk for venous thromboembolism (VTE), or blood clots, following surgery for long-bone reconstruction in patients with metastatic cancer. They published the results in the Journal of Bone and Joint Surgery. "Our study shows not only that a stronger anti-coagulation therapy may be warranted for these patients, but also that each case needs individualized attention," said senior author John A.
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