More patients opt for mastectomy despite limited, early-stage breast cancer
the ONA take:
According to a new study published in JAMA Surgey, researchers from Vanderbilt University in Nashville, Tennessee, have found that more women with breast cancer are opting for mastectomy, including double mastectomy, rather than undergoing breast conservation surgery despite having early stage disease that is limited to one breast.
For the study, researchers analyzed the records of more than 1.2 million adults women with breast cancer treated from 1998 to 2011 from the National Cancer Data Base. Of those, 35.5% underwent a mastectomy. In the 8 most recent years of the study, the odds of breast conversation surgery-eligible women opting for mastectomy increased 34%.
During the entire period of the study, the rate of double mastectomy in women with cancer in only one breast increased from 1.9% to 11.2%. During the same period, the rate of breast reconstruction in women who underwent mastectomy increased from 11.6% to 36.4%.
The researchers note that the rising rate of mastectomy was most marked among younger women with noninvasive disease, women with smaller tumors, and women with node-negative disease. The findings suggest that factors other than disease burden and cancer control are influencing women to undergo mastectomy.
More women with breast cancer are opting for mastectomy rather than undergoing breast conservation surgery.
The rates of increase were steepest among women with lymph node-negative and in situ (contained) disease. This is a reversal of trends seen since the 1990s when breast conservation surgery (BCS) was found to produce equivalent cancer outcomes and was endorsed as a standard of excellence by a National Institutes of Health Consensus Conference.
Sign Up for Free e-newsletters
- Managing Chemo Brain in Pediatric Survivors of Childhood Cancer
- Aggressive Therapy Provides No Additional Advantage in Metastatic Prostate Cancer
- Excretion of Volatile Organic Compounds Higher in AYAs Using Vaping Products
- FDA, ASHP Actions to Prevent or Manage Chemotherapy Drug Shortages
- Risk for Cardiovascular Disease Higher in Survivors of Testicular Cancer
- Various Aspects of Palliative Care Focus Associated With Different Outcomes In Cancer
- Cost vs Benefits: The Controversy Over Proton Beam Radiotherapy
- Patient Expectations at Odds With Actual Outcomes for Radiotherapy in Breast Cancer
- Patients Desire More Online Tools and Access
- Metformin Plus Ruxolitinib: A Potential Therapeutic Alternative for Myeloproliferative Neoplasms
- Sexual Quality of Life Decreased During, After Chemotherapy for Digestive Cancers
- CHEMO-SUPPORT: A Nursing Intervention to Relieve Chemotherapy Symptom Burden
- Approach and Management of Checkpoint Inhibitor-related Immune Hepatitis
- Revised AJCC8 Demonstrates Superior Tumor Classification for HNCSCC
- Oral Androgen Receptor Inhibitor Granted FDA Approval for Nonmetastatic CRPC
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|