Hyperfractionated radiation therapy may increase local-regional control for patients with head and neck cancer

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A treatment consisting of hyperfractionated radiation therapy (HFX) was shown to have improved local-regional control in patients with locally advanced squamous cell carcinoma of the head and neck. The randomized study evaluated patients, 18 and older, who received standard fractionation (SFX) compared to those that received HFX, accelerated fractionation with a split (AFX-S) or accelerated fractionation-continuous (AFX-C). An improvement in overall survival with no increase in late toxicity was also observed.

Hyperfractionated radiation therapy may increase local-regional control for patients with head and n
Hyperfractionated radiation therapy may increase local-regional control for patients with head and n
Patients with locally advanced squamous cell carcinoma of the head and neck treated with hyperfractionated radiation therapy (HFX) experienced improved local-regional control and, with patients censored at five years, improved overall survival with no increase in late toxicity, according to a study published in the May 1, 2014 edition of the International Journal of Radiation Oncology • Biology • Physics.
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