HPV vaccine may be effective with just one dose, not three

the ONA take:

One dose of the HPV vaccine may be sufficient to protect girls from cervical cancer rather than the currently recommended three doses.

Although the data is not convincing enough to change vaccination strategies immediately, reducing the number of doses needed to one could have a significant impact on how many girls would get immunized throughout the world.

The researchers from the US National Cancer Institute and elsewhere reviewed data from trials covering more than 24,000 girls to determine how long the vaccine was effective after one, two, and three doses. Vaccine effectiveness after 4 years is estimated to be 77% to 86% for all vaccinated females, regardless of how many doses they received.

Researchers theorize that the virus-like particles used to make Cervarix may have provoked a particularly strong response from the girls’ immune system.

Despite the positive results, GlaxoSmithKline PLC, the manufacturer of Cervarix, has no plans to file for a single-dose license. Health officials in Britain changed their recommendation to advise young girls receive two doses of the vaccine.

In the United States, HPV vaccines are licensed as three-dose regimens only and the top vaccine advisory committee has not discussed these data on using one dose.

HPV vaccine may be effective with just one dose, not three
One dose of the HPV vaccine may be sufficient to protect girls from cervical cancer rather than the currently recommended three doses.
Protecting girls from cervical cancer might be possible with just one dose of the HPV vaccine rather than the three now recommended, a new analysis suggests. The authors of the study acknowledged it isn't convincing enough to change vaccination strategies immediately.
READ FULL ARTICLE From Medical Express
Loading links....
You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs