Granisetron plus dexamethasone may increase arrhythmia risk
the ONA take:
According to two studies published online ahead of print in the journal BMC Medicine, researchers have found that granisetron, a serotonin 5HT3 receptor antagonist, plus dexamethasone may increase a patient's risk for developing an arrhythmia.
Most arrhythmias are no serious; however, some put patients at a higher risk for stroke, heart failure, or cardiac arrest.
Serotonin receptor antagonists, such as granisetron, ondansetron, and palonosetron, are commony used to reduce nausea and vomiting in patients receiving moderately or highly emetogenic chemotherapy, as well as in those undergoing surgery.
Results of the studies showed that the safest serotonin receptor antagonists in combination with a steroid with respect to arrhythmia were ondansetron plus dexamethasone, and dolasetron for patients of all ages.
The studies were conducted in patients undergoing anesthesia for surgery.
Granisetron plus dexamethasone may increase a patient's risk for developing an arrhythmia.
- Acupuncture an Effective Alternative Treatment for Cancer-Related Fatigue
- Compound in Teas, Peas, Soybeans May Increases Prostate Cancer Risk
- Response to Anemia Treatment Differs in Lymphoma, Multiple Myeloma
- Fertility Preservation in Male Adolescents and Young Adults With Cancer
- Social, Psychiatric Variables Reduce Cognitive Functioning, QoL in HNC
- HPV and Cancer (Fact Sheet)
- Pain Control More Easily Achieved With Nurse-Led Education in Bone Metastases
- Using Nutrition-Based Strategies to Manage Adverse Effects of Cancer
- Palliative Care Associated With Decreased Costs For Patients With Advanced Cancer
- A Case of Immunotherapy-Induced Myocarditis Concomitant to MG in Lung Cancer
- Online Learning Modules Improve Exercise Counseling, But Not Participation
- ASCO Issues Statement Addressing Alcohol and Cancer
- Duloxetine May Improve AI-Associated Joint Pain in Early Stage Breast Cancer
- Axillary Lymph Node Dissection Predictive for Lymphedema in Breast Cancer
- Drug Combination Does Not Extend Glioblastoma Survival
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|