Five New Genetic Variants Linked With Glioma Identified
the ONA take:
Five new genetic variants associated with glioma have been identified in the biggest ever study of DNA in patients within this population, according to a study published in Nature Communications.
Richard Houlston, MD, PhD, of The Institute of Cancer Research and an international team analyzed DNA from more than 5,637 patients with glioma from Europe, the United States, and Canada, and compared them with 9,158 patients without the disease.
Each variant they found was a one-letter difference in the DNA code that was associated with an increased risk of glioma in those who have it, thus bringing the total number of genetic variants linked to glioma to 12.
One variant in particular was linked with a 23% increased risk of glioblastoma, an aggressive form of glioma with an average survival of 10 to 15 months after diagnosis.
“We believe our study is the largest ever conducted of the genetics of glioma – the most common form of brain cancer – and it provides firm evidence that susceptibility to the disease is in part inherited,” Houlston said.
Five new genetic variants associated with glioma have been identified in the biggest ever study of DNA in patients within this population.
Sign Up for Free e-newsletters
- Avoiding the ED: Planned Strategies for Unplanned Urgent Cancer Care
- NP-Led Clinics Improved Phase 1 Oncology Study Operations, Outcomes
- Art as Palliative Care: Bedside Intervention Improves Pain, Anxiety, Mood in Hospitalized Cancer Patients
- Unprotected Sex After Chemotherapy
- Mindfulness Training May Improve End-of-Life Conversations in Advanced Cancer
- Study Suggests Greater Focus on the Needs of Family Caregivers of Patients With Cancer
- First Antibody-Based Treatment Regimen Approved for First-Line Treatment of Multiple Myeloma
- Increased Diabetes Risk Associated With Cancer Development
- Childhood Neuroblastoma Survivors at Risk for Psych Impairment
- Drug Classification of Trastuzumab
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|