Five New Genetic Variants Linked With Glioma Identified
the ONA take:
Five new genetic variants associated with glioma have been identified in the biggest ever study of DNA in patients within this population, according to a study published in Nature Communications.
Richard Houlston, MD, PhD, of The Institute of Cancer Research and an international team analyzed DNA from more than 5,637 patients with glioma from Europe, the United States, and Canada, and compared them with 9,158 patients without the disease.
Each variant they found was a one-letter difference in the DNA code that was associated with an increased risk of glioma in those who have it, thus bringing the total number of genetic variants linked to glioma to 12.
One variant in particular was linked with a 23% increased risk of glioblastoma, an aggressive form of glioma with an average survival of 10 to 15 months after diagnosis.
“We believe our study is the largest ever conducted of the genetics of glioma – the most common form of brain cancer – and it provides firm evidence that susceptibility to the disease is in part inherited,” Houlston said.
Five new genetic variants associated with glioma have been identified in the biggest ever study of DNA in patients within this population.
- Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer
- Acupuncture Improves Postoperative Symptoms in Women Undergoing Surgery for Breast Cancer
- Combination of Gemcitabine and New CHK1 Inhibitor Is Effective in Soft Tissue Sarcomas
- Alcohol Consumption, Particularly White Wine, Associated With Increased Risk of Melanoma
- In HER2+ Breast Cancer, Higher TIL Levels Associated With Improved OS
- Exercise is as Effective in Treating Metastatic Prostate Cancer as Medication
- Walnut Consumption Changes Gut Microbiome, Decreases Growth of Colon Cancer in Mice
- Vaccine Enters Phase I Study for Safety and Effectiveness in Multiple Myeloma
- Timing Chemotherapy Administration to Circadian Rhythm Improves Drug Effectiveness
- New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases
- Costs, Complications Higher for Women Who Undergo Second Surgery After BCS
- Omitting RT in Certain Older Women With Early Breast Cancer is Safe
- Fluorescent Nanoparticles Represent Novel Detection Method of HER2 Expression
- Assessment of Stromal Features in DCIS Requires Robustness
- Profile of Tivantinib and its Potential in the Treatment of Hepatocellular Carcinoma: the evidence to date
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|