Outcomes improving for younger patients with follicular lymphoma

the ONA take:

Patients younger than 40 years with follicular lymphoma have a median overall survival of 24 years and their outcome seems to be improving over time, according to a recent study published online ahead of print in the journal Annals of Oncology.

For the study, investigators sought to evaluate the clinical features and outcomes of younger patients with follicular lymphoma.

Researchers retrospectively analyzed data from 1,002 patients with follicular lymphoma diagnosed in Spain, Switzerland, United Kingdom, or Italy between 1985 and 2010.

Results showed that at a median follow-up of 10 years, younger patients had significantly better overall survival, cause-specific survival, and progression-free survival compared with those older than 40 years.

Researchers found that patients with a lymphoma diagnosis in the last two decades and having a Follicular Lymphoma International Prognostic Index (FLIPI) score were associated with a significantly longer progression-free survival and cause-specific survival in patients younger than 40 years. A favorable FLIPI score was significantly associated with longer overall survival.

Outcomes improving for younger patients with follicular lymphoma
Patients younger than 40 years with follicular lymphoma have a median overall survival of 24 years.
Background This study was aimed at investigating the clinical features and outcome of follicular lymphoma (FL) patients younger than 40 years, which have not been extensively investigated yet. Patients and methods One hundred and fifty-five patients younger than 40 years were retrospectively studied from a series of 1002 FL patients diagnosed in four different European Oncology Centres (Barcelona, Spain; Bellinzona, Switzerland; London, United Kingdom; Novara, Italy) from 1985 to 2010.
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