Ezetimibe/simvastatin combination not found to increase cancer risk, mortality
the ONA take:
According to a new study published in the American Journal of Cardiology, researchers have found that treatment with ezetimibe/simvastatin (Vytorin) is not linked with an elevated risk for developing cancer or an increased risk of cancer-related mortality.
Researchers identified 1,359 eligible patients for follow-up from the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study so that they could investigate new incidences of cancer and total mortality over 21 months following the end of the SEAS trial. Of the 1,359 patients, 1,194 had no history of cancer cancer.
In that portion of patients, 12 patients who received ezetimibe/simvastatin had developed cancer and 22 patients that received placebo developed cancer in the 21-month follow-up (HR 0.55, 95% CI 0.27 - 1.11). During the same period, 43 patients who received ezetimibe/simvastatin and 33 who received placebo died (HR 1.29, 95% CI 0.82 - 2.03).
Results suggest that treatment with the lipid-lowering combination was not linked with an increased risk for developing cancer or dying from cancer during the 21-month follow-up to the SEAS trial. Numerous authors reported financial disclosures with Merck & Co., the manufacturer of Vytorin.
Ezetimibe/simvastatin (Vytorin) is not linked with an elevated risk for developing cancer.
- Health Care Expansion Tied to Increased Rates of Surgical Treatment of Thyroid Cancer
- JAK1, JAK2 Inhibition Improves Outcomes in Myeloproliferative Neoplasms, But More Is Needed
- Hormone Refractory Prostate Cancer Responds to Abiraterone Acetate in Some Cases
- Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors
- Thyroid Cancer Incidence Increasing Among Younger, Hispanic, African American Populations
- Exercise, Psychological Interventions Better for Cancer Fatigue Than Medications
- ASCO Issues Global Guidance for HPV Vaccination for Cervical Cancer Prevention
- Discharge Events Improved With Standardized Inpatient Palliative Care Consultation
- Little Opposition to Early Palliative Care for Symptom Management in Pediatric Oncology
- Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors
- Rubraca Granted Accelerated FDA Approval for Advanced BRCA-positive Ovarian Cancer
- New Criteria for Appropriate Use of Bone Scintigraphy to Diagnose and Manage Prostate and Breast Cancer
- Primary Care Physicians Surveyed on Breast Cancer Screening Practices
- Low Acculturated Latina Women Reported Breast Cancer Treatment Experience Differently Than Other Groups
- Cost and Complication Rates Differ Among Early Breast Cancer Treatment Options
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|