Exercise throughout chemotherapy reduces cognitive impairment, inflammation
the ONA take:
According to a study presented at the 2015 American Society of Clinical Oncology annual meeting this week, researchers from the University of Rochester have found that patients with cancer who exercise throughout chemotherapy had reduced chronic inflammation and cognitive impairment.
For the phase III study, researchers enrolled 619 patients with early-stage cancer. Participants were randomly assigned to receive standard care (no prescribed exercise during chemotherapy) or a specialized program labelled EXCAP. Patients in the EXCAP group walked daily and used resistance bands as instructed while also wearing a pedometer to track steps walked.
Results showed that patients in the standard care group experienced reduced mobility and increased brain fogginess and memory problems. Those patients also had higher levels of blood inflammation. Subgroup analyses showed patients who received chemotherapy in 2-week cycles experienced the most benefit from EXCAP.
"To think that a very simple, low-cost, self-directed exercise prescription can create an anti-inflammatory response similar to a drug and protect against cognitive decline in people with cancer is innovative and very exciting," said Karen M. Mustian, PhD, MPH, associate professor in the University of Rochester Departments of Surgery and Radiation Oncology.
Patients with cancer who exercise throughout chemotherapy had reduced chronic inflammation and cognitive impairment.
Sign Up for Free e-newsletters
- Risk Factors for Arterial, Venous Thrombosis Differ in Polycythemia Vera
- Patient Satisfaction Ratings Can Be Negatively Impacted by Nurse Staffing Ratio
- Dietary Estrogens Reduced Efficacy of Novel Breast Cancer Therapy
- BRCA Mutation Improves Prognosis for 2-year Survival in Younger-onset TNBC
- Fosfomycin Effective Alternate for Febrile Neutropenia Prophylaxis
- Pertuzumab Regimen Approved for Adjuvant, Neoadjuvant Therapy in Specific Breast Cancers
- Common Oncologic Emergencies That Occur With Multiple Myeloma
- Artificial Sweeteners and Cancer Risk (Fact Sheet)
- Blueberry Extract May Boost Efficacy of Radiotherapy for Cervical Cancer
- Breast Implants Associated With Increased Risk of Breast Anaplastic Large-cell Lymphoma
- Survival Outcomes in Relapsed Hepatocellular Carcinoma Improved With Cabozantinib
- OS Similar With Gemcitabine Plus S-1 vs Standard Therapy for Biliary Tract Cancer
- Feasibility and Outcomes of Modified Enhanced Recovery After Surgery for Nursing Management of Aged Patients Undergoing Esophagectomy
- Urine Drug Testing Policy Can Assist Opioid Treatment Decisions
- Resolving Vaginal Dryness in Women With a History of Breast Cancer
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|