Enoxaparin may be safe for patients with cancer, brain metastases
the ONA take:
According to a new study published online in the journal Blood, researchers have found that patients with cancer and brain metastases who develop blood clots may safely receive enoxaparin, a type of low molecular weight heparin anticoagulant, without increased risk of intracranial hemorrhage.
For the study, researchers sought to assess the risk of intracranial hemorrhage, a dangerous form of bleeding in the head, associated with the administration of therapeutic doses of enoxaparin.
Researchers identified 239 patients with cancer and brain metastases. Of those, 104 received therapeutic enoxaparin and 189 were their matched controls that did not receive blood-thinning treatment.
Results showed that there were no differences in the cumulative incidence of intracranial hemorrhage at 1 year in the enoxaparin and control cohorts.
Researchers found that patients with melanoma or renal cell carcinoma had a fourfold higher risk of intracranial hemorrhage than those with lung cancer, but administration of enoxaparin did not affect that risk. The study also showed that overall survival was similar in both groups.
Patients with cancer and brain metastases who develop blood clots may safely receive enoxaparin.
- Acupuncture Improves Postoperative Symptoms in Women Undergoing Surgery for Breast Cancer
- Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer
- Alcohol Consumption, Particularly White Wine, Associated With Increased Risk of Melanoma
- Combination of Gemcitabine and New CHK1 Inhibitor Is Effective in Soft Tissue Sarcomas
- Omitting RT in Certain Older Women With Early Breast Cancer is Safe
- Walnut Consumption Changes Gut Microbiome, Decreases Growth of Colon Cancer in Mice
- Vaccine Enters Phase I Study for Safety and Effectiveness in Multiple Myeloma
- Timing Chemotherapy Administration to Circadian Rhythm Improves Drug Effectiveness
- New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases
- Baseline PSA Levels in Midlife Could Predict Risk of Lethal Prostate Cancer
- Community Breast Navigation Program Improved Breast Screening Rates in Underserved African American and Latino Women
- Live-streamed Videos Address End-of-Life Planning, Decision-making
- Metastatic Disease Linked to Patients Reporting Diminished QoL
- History of Bilateral Salpingo-oophorectomy, Hormone Replacement Therapy Are Predictive of Breast Density at Cancer Diagnosis
- Mammographically Occult Contralateral Breast Cancer Detection is Effective With Preoperative MRI
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|