Engineered Nanoparticles Prevent Bone Cancer, Strengthen Bones

the ONA take:

Nanomedicine technologies were utilized to develop a drug-delivery system that precisely targets and attacks cancer cells in the bone. It also increases bone strength and volume to prevent bone cancer progression. The drug-delivery system was developed via a research collaboration between Brigham and Women’s Hospital (BWH) and Dana-Farber Cancer Institute (DFCI). The scientists developed stealth nanoparticles made of a combination of clinically validated biodegradable polymers and alendronate, a bisphosphonate. Bisphosphonates bind to calcium, and the largest of calcium is in bones. The alendronate on the surface of the nanoparticles hone in on bone tissue, delivering drugs that kill tumor cells and stimulate healthy bone tissue growth. The study suggests that bone-targeted nanoparticle anticancer therapies may be a novel way to deliver a concentrated amount of drug in a controlled and target-specific manner, said a co-senior study author.

Engineered Nanoparticles Prevent Bone Cancer, Strengthen Bones
Engineered Nanoparticles Prevent Bone Cancer, Strengthen Bones
A research collaboration between Brigham and Women's Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) has utilized nanomedicine technologies to develop a drug-delivery system that can precisely target and attack cancer cells in the bone, as well as increase bone strength and volume to prevent bone cancer progression.
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