Potential biomarkers of early pancreatic cancer discovered
the ONA take:
Patients with pancreatic cancer face a poor prognosis, as only approximately 6% of patients with pancreatic cancer survive more than 5 years after diagnosis.
The low survival rate is primarily because no reliable tools are available to make an early diagnosis, when tumors can be removed before they metastasize. A team at H. Lee Moffitt Cancer Center, in Tampa, Florida, may have found a potential biomarker for the disease.
Similar to ongoing work at other research centers, the Moffitt team is focusing on microRNAs, small molecules that control many cancer processes in the body.
The Moffitt team focused specifically on microRNAs linked to intraductal papillary mucinous neoplasms (IPMNs). IPMNs are a type of pancreatic cyst or lesion that can develop into pancreatic cancer the same way precancerous polyps in the colon develop into colon cancer.
These lesions can be seen on CT or MRI; however, imaging studies cannot determine if the lesions are benign or malignant. In addition, surgical resection of the lesions for biopsy can result in long-term diabetes or death. The Moffitt team identified six microRNAs that appeared to differentiate high-risk from low-risk lesions; they also appear to contribute to pancreatic cancer progression.
Researchers are hopeful that these findings will contribute to new ways of detecting the disease earlier and improving the poor prognosis for these patients.
Patients with pancreatic cancer face a poor prognosis, as only approximately 6% of patients survive.
- Study Identifies Factors Associated With Hearing Loss in Polycythemia Vera
- High Symptom Burden With Polycythemia Vera Linked to QoL Impairment
- Bioimpedence Spectroscopy Improves Early Detection of Breast Cancer-Related Lymphedema in At-Risk Patients
- Ezh2 Inhibitors May Offer Cure for Chronic Myelogenous Leukemia
- MRD Negativity Associated With Prolonged Survival in Myeloma
- Overall Benefits of Vaporized Nicotine Products Outweigh Harms, Says International Panel of Experts
- Sugar and Cancer: Mitigating the Affects of Diet on Cancer
- Nurse Residency Programs Can Impact Oncology Nursing Practice, Outcomes
- Tumor Markers (Fact Sheet)
- Implementing a Distress Screening Process for Cancer Patients
- ASCO, ASTRO Issue Guideline Update for Postmastectomy RT
- Study Assesses Efficacy of Ramucirumab in HCC by Child-Pugh Score
- Incontinence Affects QOL for Survivors of Gynecologic Cancers
- Patient Navigation Reduces Delays in Diagnostic Resolution
- Fee-for-service Medicare Plans Linked to Improved Care During Last Year of Life
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|