Direct injection treatment of pancreatic cancer shows encouraging results

the ONA take:

Results of a phase I clinical trial of a vaccine therapy for pancreatic cancer indicate the treatment is well tolerated; in addition, it suggests that the vaccine stabilizes the disease for a period of time. The study was conducted at Rutgers Cancer Institute of New Jersey. In a previous study, investigators demonstrated that vaccine therapy was effective in reversing the immune blockade in laboratory models of bladder and breast cancer tumors. Building on that research, this study involved two types of the PANVAC investigational vaccine. The first, PANVAC-V is a live but weakened vaccinia vaccine administered by injection in the arm. The other is PANVAC-F, which is injected into the tumor itself and subsequently into the arm as a booster. Direct tumor injection is achieved via endoscopic ultrasonography through the mouth and into the stomach. Of the 10 patients who completed the trial, three were shown to have distant metastatic disease with a survival range of 6 to 22 months. The other seven patients had no metastatic disease and a survival range of 4 to 36 months. Given the poor prognosis of this disease, the researchers were encouraged by these results.

Direct injection treatment of pancreatic cancer shows encouraging results
Direct injection treatment of pancreatic cancer shows encouraging results
Research from Rutgers Cancer Institute of New Jersey shows that the ‘first in man' series of vaccine injections given directly into a pancreatic cancer tumor is not only well tolerated, but also suggests an“encouraging” period of stable disease. Building on this research, investigators further ...
Loading links....
You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs