Diet swap study suggests it may never be too late to modify colon cancer risk
the ONA take:
According to a new study published in the journal Nature Communications, African-Americans and Africans who swapped their usual diets for 2 weeks also exchanged their respective colon cancer risks as a result of alterations to their gut flora.
For the study, 20 African-American and 20 rural South African volunteers ate meals typical of the other group for 2 weeks.
Analyses of fecal and colon content samples showed that each group took on the other's rates of turnover of intestinal lining cells, levels of fiber fermentation, and biomarkers of inflammation and bacterial metabolic activity that are linked with colon cancer risk.
The African-American diet, which consists of more animal protein and fat, and less soluble fiber than the typical African diet is thought to increase the risk for colon cancer.
"These findings are really very good news," said principal investigator Stephen O'Keefe, M.D. professor of medicine, Division of Gastroenterology, Hepatology and Nutrition at the Pitt School of Medicine. "In just two weeks, a change in diet from a Westernized composition to a traditional African high-fiber, low-fat diet reduced these biomarkers of cancer risk indicating that it is likely never too late to modify the risk of colon cancer."
African-Americans who swapped their usual diets for 2 weeks also exchanged their respective colon cancer risks.
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