Common virus kills triple-negative breast cancer

the ONA take:

A virus that commonly infects humans without causing sickness has been observed destroying triple-negative breast cancer cells and killing tumors grown from these cells in mice. In a study published in the Cancer Biology & Therapy journal, researchers studied the effect of Adeno-associated virus type 2 (AAV2) on human breast cancer cell line-derived tumors in mice and on a cell-line representative of triple-negative breast cancer.

The results were promising: tumor size in mice treated with AAV2 decreased, areas of cell death were visible, and the AAV2-treated mice outlived the control mice and displayed no symptoms of their disease. The cancer cells infected with the AAV2 produced more of the protein Ki-67, stimulating the immune system, and activated caspases, triggering apoptosis (cell death). The researchers feel the next research step would be an analysis of the body-wide effect on mice, which might serve as a better example of possible human end results.

Common virus kills triple-negative breast cancer
Common virus kills triple-negative breast cancer
A virus not known to cause disease kills triple-negative breast cancer cells and killed tumors grown from these cells in mice, report researchers. Adeno-associated virus type 2 (AAV2) infects humans but is not known to cause sickness. Signaling pathways involve molecules in a cell that control cell functions—such as cell division—by cooperation.
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