Patients with diabetes receiving treatment for CRC may experience more neuropathic symptoms

the ONA take:

Patients with colorectal cancer who also have diabetes experienced more neuropathic symptoms, regardless of cancer treatment, according to a recent study published in the Journal of Cancer Survivorship.

Researchers found that patients with colorectal cancer and diabetes experienced more mild to severe neuropathic symptoms, including tingling fingers or hands, tingling toes or feet, numbness in toes or feet, and erectile dysfunction among men, than patients without diabetes.

The study demonstrated no differences in cancer treatment between patients with colorectal cancer and diabetes compared with those without diabetes.

The authors conclude that diabetes rather than chemotherapy results in more neuropathic symptoms among patients with cancer and diabetes compared with those without diabetes.

The findings ultimately suggest that up to 39% of cancer survivors might expect mostly mild, neuropathic symptoms, with more symptoms occurring in patients with diabetes. 

Neuropathic symptoms are typically associated with the chemotherapy agent oxaliplatin, which is often used in combination with fluorouracil, leucovorin, and sometimes irinotecan in the treatment of colorectal cancer.

Some older adults with diabetes overtreated for their disease
Patients with colorectal cancer who also have diabetes experienced more neuropathic symptoms, regardless of cancer treatment.
This study assessed differences in neuropathic symptoms between colorectal cancer (CRC) patients with and without diabetes. Moreover, we aimed to explore whether neuropathic symptoms could be explained by the receipt of chemotherapy as it was previously shown that cancer patients with diabetes less often receive chemotherapy.
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