Buccal fentanyl may be valid option during placement of indwelling central venous access port
the ONA take:
Fentanyl buccal tablet is a valid, practical, and safe method of procedural analgesia for patients with cancer during placement of indwelling central venous access systems, a new study published online ahead of print in the journal Supportive Care in Cancer has shown.
Although local anesthesia is most commonly used to overcome pain related to the procedural placement of fully implantable venous access systems in patients with cancer, it may not eradicate all pain. Therefore, researchers sought to evaluate the effectiveness and safety of fentanyl buccal tablet in reducing procedural pain related to the placement of the port in opioid-naïve patients.
For the study, researchers enrolled 65 inpatients who required an indwelling vascular access port. Patients received a 100-mcg fentanyl buccal tablet 10 minutes before preparation of the operating field.
Results showed that nearly 94% of patients experienced no or little pain during the procedure. Only four patients reported a lot of pain, and no patients reported very severe pain.
In regard to safety, 43.1% experienced drowsiness, 9.2% experienced nausea, and 4.7% experienced vomiting, at the end of the procedure. Four hours after the procedure, the rates of drowsiness, nausea, and vomiting were 12.5%, 10.9%, and 7.8%, respectively.
“It will be necessary to perform further studies, taking into account the need for standard antiemetic premedication to [minimize] the incidence of nausea and vomiting,” the authors conclude.
Fentanyl buccal tablet is a valid, practical, and safe method of procedural analgesia for patients with cancer.
- Immunotherapy May Benefit Some Patients with Papillary Thyroid Carcinoma
- Screening Recommendations for Children with Common Cancer Predisposition Syndromes
- Significance of Prostate Cancer Treatment-Related Factors Differ in Black, White Men
- New Study Questions Standard Dosage for Treating Metastatic Non-Small Cell Lung Cancer
- Superior Tolerability, Efficacy With Alectinib in Treatment-Naïve ALK-poistive NSCLC
- Survivorship Care Plans: Providing A Blueprint for Health Care After Cancer
- Cancer Recurrence Fear Reduced by Novel Psychological Intervention
- Multifaceted Role of the Nurse Navigator Includes Palliative, Supportive Care
- Patient Navigators Found to Boost Lung Cancer Screening Rates
- Lack of Transfusion Services a Barrier to Hospice Care for Patients With Blood Cancers
- Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes
- Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups
- Study Questions Safety of E-cigarettes vs Regular Tobacco Cigarettes
- Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study
- Increases in Liver Cancer Incidence Influenced by Higher Rates of Comorbidities
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|