Infection may cause breast implant-associated anaplastic large cell lymphoma

the ONA take:

According to new findings by researchers at Macquarie University's Australian School of Advanced Medicine in New South Wales, Australia, a bacterial infection on the surface of textured breast implants may elevate the risk for developing anaplastic large cell lymphoma.

Previous studies have found that anaplastic large cell lymphoma, a rare type of cancer, is associated with breast implants. Other studies have shown that bacterial infections on the biofilm of breast implants can cause capsular contracture, thereby causing pain and physical deformity around the implant. Now, researchers have found that chronic bacterial infection around the breast implants can ultimately activate the person's immune system and lymphocytes.

The researchers hypothesize that the long-term stimulation of lymphocytes triggered by chronic bacterial infection may cause these cells to transform into anaplastic large cell lymphoma. In addition, people with textured breast implants were found to have the highest amount of infection, which may explain why breast implant-associated anaplastic large cell lymphoma is more often observed in patients with textured implants.

The findings suggest the importance of reducing the risk of breast implant infection as the number of reported cases of breast implant-associated anaplastic large cell lymphoma is on the rise.

Infection may cause breast implant-associated anaplastic large cell lymphoma
Bacterial infection on the surface of textured breast implants may elevate the risk for large cell lymphoma.

New research has revealed that infection by bacteria on the surface of textured breast implants may increase women's risk of developing a rare type of cancer – newly designated as breast implant associated anaplastic large cell lymphoma (BIA-ALCL).

Previous studies led by Associate Professor Anand Deva of Macquarie University's Australian School of Advanced Medicine have found that bacteria which live in clumps attached to breast implants (termed biofilm), is a major cause of capsular contracture. Contracture is a painful hardening of the tissue around the implant that can cause physical deformity, pain and is the most common cause for revision surgery following breast augmentation.

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