Chemotherapy less likely to benefit older patients with breast cancer
the ONA take:
Examining data from Surveillance, Epidemiology and End Results (SEER) database, researchers from The University of Texas Health Science Center at Houston (UTHealth) found that chemotherapy does not improve survival for older women with breast cancer.
SEER database provided information on 14,440 women with stage I to IIIA hormone receptor-negative breast cancer and 26,893 men and women with stage III colon cancer. All diagnoses were made between 1992 and 2009, and all patients were older than 65 years.
Risk of death from all causes decreased by age among the women who had breast cancer (30% for women ages 65 to 69 years; 26% for ages 70 to 74 years; 24% for ages 75 to 79). The risk of mortality was not significantly reduced for women older than 80 years.
However, this trend was not seen among men and women with colon cancer. Chemotherapy remained effective for these patients until age 89 years.
The investigators noted that previous research showed that chemotherapy is inefficient in patients older than 70 years with breast cancer, but the sample sizes were small. The larger sample size used in this study provides strong evidence to support this finding.
Chemotherapy does not improve survival for older women with breast cancer.
- Immunotherapy May Benefit Some Patients with Papillary Thyroid Carcinoma
- Screening Recommendations for Children with Common Cancer Predisposition Syndromes
- Significance of Prostate Cancer Treatment-Related Factors Differ in Black, White Men
- New Study Questions Standard Dosage for Treating Metastatic Non-Small Cell Lung Cancer
- Superior Tolerability, Efficacy With Alectinib in Treatment-Naïve ALK-poistive NSCLC
- Survivorship Care Plans: Providing A Blueprint for Health Care After Cancer
- Cancer Recurrence Fear Reduced by Novel Psychological Intervention
- Multifaceted Role of the Nurse Navigator Includes Palliative, Supportive Care
- Patient Navigators Found to Boost Lung Cancer Screening Rates
- Lack of Transfusion Services a Barrier to Hospice Care for Patients With Blood Cancers
- Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes
- Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups
- Study Questions Safety of E-cigarettes vs Regular Tobacco Cigarettes
- Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study
- Increases in Liver Cancer Incidence Influenced by Higher Rates of Comorbidities
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|