Many patients with locally advanced breast cancer do not undergo recommended postmastectomy radiotherapy
the ONA take:
Patients with breast cancer who undergo a mastectomy should receive subsequent postmastectomy radiation therapy (PMRT), which is found to reduce the risk of breast cancer recurrence and improve survival in patients with locally advanced breast cancer with a pathological stage of N2 or N3.
However, only 65% of these patients are receiving the postsurgical radiation therapy, which is the standard of care. In this study, researchers from Louisiana State University (LSU) Health Sciences Center in Shreveport evaluated compliance with the treatment guidelines using the National Cancer Data Base (NCDB).
They reviewed 56,990 de-identified files from NCDB of women with N2 or N3 cancer to determine factors linked to receipt of PMRT.
Their review revealed that only three factors independently predicted a higher likelihood that patients would receive PMRT: receipt of chemotherapy, readmission to the hospital within the first month after mastectomy, and being alive 30 days after the surgery.
In addition, this study highlighted an important issue regarding implementing new research findings into clinical practice.
On average, the time from when a new intervention is recommended as evidence-based practice to full adoption in the clinical setting is 9 years.
Only 65% of patients with advanced breast cancer are receiving the postsurgical radiation therapy.
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