Disparities persist in breast cancer, regardless of stage, subtype

the ONA take:

A consistent observation in studies on breast cancer is that minority women, especially African Americans, Hispanic whites, and American Indians, are more likely to have a advanced stage breast cancer at diagnosis, their treatment is less likely to follow recommended regimens, and they are more likely to die of their disease.

Previous studies addressed disparities by stage of disease and survival rates, but none of them characterized the patients by disease subtype.

Lu Chen, MPH, at Fred Hutchinson Cancer Research Center in Seattle, Washington, and colleagues conducted research on incidence of breast cancer subtypes among various ethnic and racial groups. Their research was published in Cancer Epidemiology, Biomarkers & Prevention.

Chen and colleagues reviewed data from 18 US population-based cancer registries participating in the Surveillance, Epidemiology, and End Results (SEER) program.

In addition to demographic, cancer, and health insurance information on 102,064 US women, the researchers gathered data on tumor subtypes, hormone receptor (HR) status, and human epidermal growth factor 2-neu (HER2) status.

Their research showed that non-Hispanic white women were more likely to have smaller tumors and less aggressive disease, whereas African American women had larger tumors, more aggressive disease, and their disease was more likely to be at a later stage at diagnosis.

Furthermore, compared with non-Hispanic whites, women of all other racial and ethnic groups had more advanced disease at diagnosis.

“We found that there is a consistent pattern of late diagnosis and not receiving recommended treatment for some racial and ethnic groups across all breast cancer subtypes,” Chen said in an interview.

Team publishes initial data from TAILORx breast cancer trial
Previous studies addressed disparities by stage of disease and survival rates, but none of them characterized the patients by disease subtype.
It has been consistently observed that minority women, especially African Americans, Hispanic whites and American Indians, are more likely to be diagnosed at advanced stages of breast cancer, less likely to receive recommended treatment regimens, and more likely to die of the disease.
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