Head And Neck Cancer

USPSTF Continues Recommendations Against Thyroid Cancer Screening

USPSTF Continues Recommendations Against Thyroid Cancer Screening

Widespread routine thyroid cancer screening can lead to overdiagnosis and overtreatment, the USPSTF contends.

Metabolic Syndrome Associated With Increased Risk of Esophageal Cancer in Older Patients

Metabolic Syndrome Associated With Increased Risk of Esophageal Cancer in Older Patients

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A retrospective evaluation investigated the association between risk of esophageal cancer, metabolic syndrome, Barrett esophagus, and GERD in older persons.

Smoking-related Cancer Deaths Highest in Southern United States

Smoking-related Cancer Deaths Highest in Southern United States

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Smoking-attributable cancer mortality estimates have not been established by state; therefore, in this study, the proportion of cancer deaths among persons 35 years and older related to cigarette smoking in 2014 was calculated for each state and DC.

Outcomes Are Better for HPV16-Associated Oropharyngeal Cancer, but Not for Other HPV Strains

Outcomes Are Better for HPV16-Associated Oropharyngeal Cancer, but Not for Other HPV Strains

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Patients with oropharyngeal tumors that harbor HPV16 have higher 5-year survival and lower recurrence rates than patients with tumors that harbor other HPV strains or are HPV-negative.

Definitive IMRT Associated With Shorter Feeding Tube Placement Duration in HNC

Definitive IMRT Associated With Shorter Feeding Tube Placement Duration in HNC

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Patients with head and neck cancer treated with IMRT had a significantly shorter duration of feeding tube placement compared with those who received 3DRT.

Robotic Surgery Provides Good Outcomes and Survival in Oropharyngeal Cancer

Robotic Surgery Provides Good Outcomes and Survival in Oropharyngeal Cancer

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Transoral robotic surgery (TORS) with or without radiation therapy or chemotherapy is an effective treatment option for patients with oropharyngeal cancer regardless of their p16 status.

Poor Oral Health Associated With OPSCC Regardless of HPV Status

Poor Oral Health Associated With OPSCC Regardless of HPV Status

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Despite a higher risk for HPV-negative orophayngeal squamous cell carcinoma (OPSCC), poor oral health appears to be associated with OPSCC regardless of HPV status.

Gemcitabine Plus Cisplatin Prolongs PFS in Nasopharyngeal Cancer

Gemcitabine Plus Cisplatin Prolongs PFS in Nasopharyngeal Cancer

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Gemcitabine in combination with cisplatin is associated with a significant improvement in progression-free survival in nasopharyngeal carcinoma.

Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma

Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma

[OncoTargets and Therapy] This research reviews the effects of single-port access transaxillary totally endoscopic thyroidectomy on outcomes following surgery, including quality of life and cosmetic result, in patients with papillary thyroid carcinoma (PTC).

Cabozantinib May Be More Effective in Patients With Certain Mutations

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Patients with medullary thyroid cancer who harbor RET M918T or RAS mutations may derive greater clinical benefit from cabozantinib compared with patients who do not have those genetic mutations.

Study Evaluates Systemic Therapy Use With RT Among Older Patients With Head and Neck Cancer

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In contrast of available prospective data, most older patients with locoregionally advanced head and neck cancer are treated with definitive radiotherapy also receive systemic therapy.

Chemoradiation Combination Could Preserve Larynx in Patients With Laryngeal and Hypolaryngeal Cancer

Chemoradiation Combination Could Preserve Larynx in Patients With Laryngeal and Hypolaryngeal Cancer

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Researchers assessed the rates of laryngeal preservation and laryngectomy-free survival in patients with laryngeal or hypopharyngeal cancer who received the monoclonal antibody cetuximab and radiation therapy or radiation therapy alone.

Methadone May Be Superior to Fentanyl for Neuropathic Pain

Methadone May Be Superior to Fentanyl for Neuropathic Pain

Methadone appears to be superior to fentanyl for the treatment of neuropathic pain in patients with head and neck cancer.

Medicaid Insurance Linked to Worse Head and Neck Cancer Outcomes

Medicaid Insurance Linked to Worse Head and Neck Cancer Outcomes

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A recent study examined the possible correlation between Medicaid coverage status and overall survival for patients with head and neck cancer.

Transforming the Care of Patients With Thyroid Cancer

Transforming the Care of Patients With Thyroid Cancer

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There were no effective therapeutic options for advanced thyroid cancer until 5 years ago.

Incidence of Oropharyngeal Cancer Increasing Among Older Patients

Incidence of Oropharyngeal Cancer Increasing Among Older Patients

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The incidence of oropharyngeal squamous cell carcinoma is increasing among older patients residing in the United States, likely due to the increase in HPV-associated malignancies.

Broccoli Sprout Extracts May Prevent Recurrence of Some Oral Cancers

Broccoli Sprout Extracts May Prevent Recurrence of Some Oral Cancers

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Beverages derived from broccoli sprout extracts were found to have preclinical chemopreventive activity against oral cancer induced by carcinogens.

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

Investigation of a Novel Method for Managing Oral Cancer Pain Is Awarded NIDCR Grant

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Quality of life for patients with oral cancer can be dismal due to cancer-related pain. An NIDCR grant is supporting the investigation of a nonviral gene delivery method for treating oral cancer pain safely and effectively.

New Nanoplatform Improves Drug Delivery in Anaplastic Thyroid Cancer

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Scientists developed an innovative nanoplatform to more effectively deliver RNA interference to anaplastic thyroid cancer (ATC) sites. ATC is the most aggressive form of thyroid cancer; mortality is almost 100% and median survival is 3 to 5 months.

Stepped Care Effective for Psychological Distress

Stepped Care Effective for Psychological Distress

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Stepped care is effective and reduces recovery time among patients with head and neck cancer or lung cancer and untreated psychological distress.

Nimotuzumab + Radiotherapy Less Toxic Than Cisplatin + Radiotherapy for Stage III/IVB Nasopharyngeal Cancer

Nimotuzumab + Radiotherapy Less Toxic Than Cisplatin + Radiotherapy for Stage III/IVB Nasopharyngeal Cancer

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Patients with locally advanced nasopharyngeal cancer concurrently treated with nimotuzumab and radiotherapy had similar rates of progression-free and overall survival to those treated with cisplatin and radiotherapy, but with significantly fewer GI and hematologic toxicities, according to phase 3 trial results presented at the ASCO 2016 Annual Meeting.

Cisplatin, Cetuximab Show Similar Locoregional Control in Unresectable Head and Neck Cancer

Cisplatin, Cetuximab Show Similar Locoregional Control in Unresectable Head and Neck Cancer

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Survival results from the first randomized phase 3 trial to compare cisplatin-radiotherapy with cetuximab-radiotherapy after induction chemotherapy in patients with locally advanced unresectable head and neck cancer remain inconclusive, with both arms showing good locoregional control, greater than 50% at 3 years, attendees at the ASCO 2016 Annual Meeting were told.

Concurrent Chemoradiotherapy Remains Standard of Care in Locally Advanced SCCHN

Concurrent Chemoradiotherapy Remains Standard of Care in Locally Advanced SCCHN

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A phase 3 noninferiority study has found that in patients with nonoperable locally advanced squamous cell cancer of the head and neck, concurrent chemoradiotherapy remains the standard treatment, according to results presented at the ASCO 2016 Annual Meeting.

Survival in Head and Neck Cancer Increased With Nivolumab Over Chemotherapy

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The immunotherapy drug nivolumab conferred a survival benefit in patients with head and neck cancer over standard chemotherapy.

MASCC Tool Improves Documentation of Dermatologic Toxicities of TKIs

MASCC Tool Improves Documentation of Dermatologic Toxicities of TKIs

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Incorporating a modified MASCC grading tool for evaluating epidermal growth factor receptor inhibitor (EGFRI) toxicities and quality of life improved the rate of skin assessments and documentation.

Oncology Nurse-led Team Can Reduce Treatment Delays, Hospitalizations for Patients With Head and Neck Cancer

Oncology Nurse-led Team Can Reduce Treatment Delays, Hospitalizations for Patients With Head and Neck Cancer

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An oncology nurse-led team approach can reduce treatment delays and hospitalizations and improve quality of care for patients with head and neck cancer.

Targeted Therapy Enhances Chemotherapy, Improves Outcomes in Retinoblastoma

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The effectiveness of chemotherapy was enhanced by targeting survivin, a protein that inhibits apoptosis or cell death, according to preclinical research in cells and mouse models of retinoblastoma.

30-day Readmission After Parotid Cancer Surgery Linked to Increased 30-day Mortality Risk

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Having an unplanned readmission within 30 days of undergoing definitive surgery is associated with increased risk of 30-day mortality among patients with previously untreated parotid cancer.

Radioactive Iodine Treatment Affects Fertility in Women With Thyroid Cancer

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In women of reproductive age who have thyroid cancer, their remaining egg supply is affected by radioactive iodine treatment, potentially reducing their fertility.

Older Age Patients with HNSCC Benefit from Afatinib vs Methotrexate

Older Age Patients with HNSCC Benefit from Afatinib vs Methotrexate

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Patients age 65 years or older with recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) did not have worse clinical outcomes.

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