Head And Neck Cancer

Negative Margins, Lymph Node Yields Predict Survival

Negative Margins, Lymph Node Yields Predict Survival

Patients with head and neck cancer treated at hospitals attaining the combined metric of a 90 percent or higher negative margin rate and 80% percent of cases achieving a LNY of 18 or more experienced a significant reduction in mortality.

De-escalated Radiation Therapy Improves Quality of Life in Throat Cancer

De-escalated Radiation Therapy Improves Quality of Life in Throat Cancer

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Aggressive de-escalation of chemoradiation after surgery in patients with HPV-associated OPSCC led to similar disease control and improved quality of life and safety profile compared with historical controls, according to data presented at the ASTRO 59th Annual Meeting.

Distress Assessments Improve Psychosocial Support Referrals for HNC Patients

Distress Assessments Improve Psychosocial Support Referrals for HNC Patients

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A quality improvement project demonstrates that routine distress assessment using the NCCN DT/PL in patients with head and neck cancers improves referrals for psychosocial services.

Most Skull Radiation Patients Show No Cognitive Impairment

Most Skull Radiation Patients Show No Cognitive Impairment

The researchers found that the majority of patients had no frank detectable cognitive impairment after undergoing skull base irradiation.

Resistance Training, Nutritional Interventions Prevent Muscle Loss During, After Radiotherapy for Head and Neck Cancer

Resistance Training, Nutritional Interventions Prevent Muscle Loss During, After Radiotherapy for Head and Neck Cancer

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Intervention with resistance training and nutritional supplements during and after radiation therapy is not only feasible, but also shown to prevent loss of muscle mass and improve quality of life in patients with head and neck cancer (HNC).

Risk of Thyroid Cancer Increased With Fruit Juice Consumption, No Effect With Fruit and Vegetable Consumption

Risk of Thyroid Cancer Increased With Fruit Juice Consumption, No Effect With Fruit and Vegetable Consumption

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No correlation was found between fruit and vegetable consumption and the risk of differentiated thyroid cancer, but a positive trend may be associated with fruit juice intake.

Lenvatinib Improves OS, PFS in Radioiodine-Refractory Differentiated Thyroid Cancer in All Older Patients

Lenvatinib Improves OS, PFS in Radioiodine-Refractory Differentiated Thyroid Cancer in All Older Patients

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Results from a sub-analysis of the impact of age on the safety and efficacy of lenvatinib in patients with RR-DTC in the SELECT trial showed that lenvatinib significantly increased PFS.

Immunotherapy May Benefit Some Patients with Papillary Thyroid Carcinoma

Immunotherapy May Benefit Some Patients with Papillary Thyroid Carcinoma

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Immunotherapy regimens FDA-approved for the treatment of melanoma may also be an option for a rare and aggressive form of papillary thyroid cancer.

Pembrolizumab Use With CRT Safe in Locally Advanced HNSCC

Pembrolizumab Use With CRT Safe in Locally Advanced HNSCC

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Small study also showed that pembrolizumab does not significant impair radiation or chemotherapy dosing.

Adjuvant + Neoadjuvant Pembrolizumab Safe in Patients Undergoing HNSCC Surgery

Adjuvant + Neoadjuvant Pembrolizumab Safe in Patients Undergoing HNSCC Surgery

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Study also provides evidence supporting an anti-tumor effect associated with a single preoperative dose of pembrolizumab.

ESW Technique Improves Nanoparticle Drug Delivery to Solid Tumors with Restricted Blood Flow

ESW Technique Improves Nanoparticle Drug Delivery to Solid Tumors with Restricted Blood Flow

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Combining extracorporeal shock wave (ESW) technique with nanoparticle delivery improves treatment of difficult-to-treat solid tumors, such as anaplastic thyroid cancer.

The United States Services Task Force (USPSTF) Recommends Against Thyroid Cancer Screening

The United States Services Task Force (USPSTF) Recommends Against Thyroid Cancer Screening

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Although screening is often recommended as the first line of prevention for most cancers, recent recommendation from the USPSTF advises against thyroid cancer screening in nonsymptomatic adults.

Survivorship Care Plans Specific to Head and Neck Cancers Enable Transition to Posttreatment Care

Survivorship Care Plans Specific to Head and Neck Cancers Enable Transition to Posttreatment Care

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Disease-specific survivorship care plans (SCPs) for head and neck cancer support a successful transition to a healthy lifestyle after curative intent therapy of larynx and oral cavity/pharynx cancer.

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

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A literature review noted improvements in quality of life after patients were coached and educated following radiotherapy for HPV-associated oropharyngeal cancers.

ASTRO Guideline Addresses Curative Treatment of Oropharyngeal Cancer

ASTRO Guideline Addresses Curative Treatment of Oropharyngeal Cancer

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Clinical practice guideline from ASTRO addresses optimal radiation doses and fractionation schedules, integrating therapies, and induction chemotherapy for oropharyngeal squamous cell carcinoma (OPSCC).

Health Care Expansion Tied to Increased Rates of Surgical Treatment of Thyroid Cancer

Health Care Expansion Tied to Increased Rates of Surgical Treatment of Thyroid Cancer

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Thyroid is more likely to be managed with surgical intervention when patients have access to expanded health insurance.

Thyroid Cancer Incidence Increasing Among Younger, Hispanic, African American Populations

Thyroid Cancer Incidence Increasing Among Younger, Hispanic, African American Populations

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A report on incidence of thyroid cancer shows incidence of the disease is increasing among certain populations: younger persons, Hispanic, and African American.

Continuing Nivolumab After Progression of Head and Neck Cancer May Improve Survival

Continuing Nivolumab After Progression of Head and Neck Cancer May Improve Survival

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Continuing immunotherapy after disease progression extends survival for some patients with head and neck cancer.

Presence of Protein E6 Predictive of Oropharyngeal Cancer Risk in HPV16-Infected Persons

Presence of Protein E6 Predictive of Oropharyngeal Cancer Risk in HPV16-Infected Persons

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Protein produced by chronically infected cells in persons with HPV16 infection serves as a biomarker for risk of cancer of the oropharynx.

Thymomas Trigger Newly Described Autoimmune Endocrine Disease

Thymomas Trigger Newly Described Autoimmune Endocrine Disease

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Thymomas can result in a newly described autoimmune disease, potentially leading to hypopituitarism,

No Intervention for Small Thyroid Cancers May Cause Anxiety

No Intervention for Small Thyroid Cancers May Cause Anxiety

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Deciding not to intervene for small, incidentally identified thyroid cancer may cause patients to experience anxiety and feelings of isolation.

HPV Vaccination Discussions Need to Focus on Education, Awareness

HPV Vaccination Discussions Need to Focus on Education, Awareness

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The top reasons for not initiating HPV vaccination are necessity, safety, and knowledge, rather than a lack of discussions on sexuality.

ASCO Endorses ACS Head and Neck Survivorship Care Guideline

ASCO Endorses ACS Head and Neck Survivorship Care Guideline

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ASCO endorses ACS head and neck survivorship care guideline, which supports health promotion, especially regarding tobacco cessation and dental care.

Nurse Navigators Improve Physician Engagement in Pretreatment Discussions

Nurse Navigators Improve Physician Engagement in Pretreatment Discussions

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Oncology nurse navigators improved physician engagement in multidisciplinary discussions prior to the initiation of treatment for patients with head and neck cancer.

Single Chemotherapy Dose Informs Treatment Strategy for Advanced Laryngeal Cancer

Single Chemotherapy Dose Informs Treatment Strategy for Advanced Laryngeal Cancer

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A new approach in which patients receive a single dose of chemotherapy may greatly improve the laryngeal cancer survival rate.

HNSCC Survival Worse for Patients in Lower Socioeconomic Population

HNSCC Survival Worse for Patients in Lower Socioeconomic Population

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Investigators determined the impact of socioeconomic status on disease status at presentation and survival among patients with head and neck squamous cell carcinoma.

Oral SCC Diagnosis Has Greater Affect on Sexual Behavior Than HPV Status

Oral SCC Diagnosis Has Greater Affect on Sexual Behavior Than HPV Status

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The impact of oral squamous cell carcinoma (OSCC) diagnosis and treatment on sexual behavior and relationship stress with respect to HPV status was evaluated in this study. Participants included patients with HPV-positive and HPV-negative disease, as well as partners.

Bioselection-individualized Treatment Modality Selection Improves Advanced Laryngeal Cancer Survival

Bioselection-individualized Treatment Modality Selection Improves Advanced Laryngeal Cancer Survival

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Multivariate analysis indicates that disease-specific survival of individuals with advanced laryngeal cancer was improved for those receiving neoadjuvant therapy.

High CVD Risk in Patients With Head, Neck Squamous Cell Cancer

High CVD Risk in Patients With Head, Neck Squamous Cell Cancer

Twenty-three percent of patients with HNSCC had CVD at the time of their diagnosis.

Cancer Cachexia Associated With Poor Outcomes

Cancer Cachexia Associated With Poor Outcomes

Findings at 6 and 12 months after treatment for advanced head and neck cancer indicate a higher risk of recurrences for those reporting cachexia after their treatment.

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