Head and Neck Cancer News & Features

Radiotherapy after tonsillectomy ups survival in early tonsil carcinoma

Radiotherapy after tonsillectomy ups survival in early tonsil carcinoma

Overall, disease-specific survival is up for patients who undergo tonsil resection rather than biopsy.

USPSTF: Evidence Is Lacking for Oral Cancer Screenings

USPSTF: Evidence Is Lacking for Oral Cancer Screenings

Task force says more work is needed to see if tests can accurately detect oral cancer and improve outcomes.

BRAF V600E mutation increases papillary thyroid cancer mortality

BRAF V600E mutation increases papillary thyroid cancer mortality

For patients with papillary thyroid cancer (PTC), the presence of the BRAF V600E mutation is associated with increased cancer-related mortality.

Erlotinib doesn't hurt but doesn't help standard head-and-neck therapy

Adding erlotinib did not increase treatment toxicity in squamous cell carcinoma of the head and neck, but it also did not improve survival.

Researchers document molecular tumor subtypes of head and neck cancer

HNSCC is the seventh most common form of cancer in the United States. However, other than an association with HPV, no validated molecular profile of the disease has been established. By analyzing data from DNA microarrays, a study has confirmed the presence of four molecular classes of the disease.

Risk-based chemotherapy effective for retinoblastoma

Risk-based chemotherapy effective for retinoblastoma

Using a classification strategy, all patients were event-free at a median 71 months of follow-up.

New drug combination could prevent head and neck cancer in high-risk patients

A new drug combination shows promise in reducing the risk of developing squamous cell carcinoma of the head and neck (SCCHN) for patients with advanced oral precancerous lesions.

Mucosal vaccination may be best route for fighting head, neck tumors

Therapeutic vaccines for mucosal cancers may work best when administered directly at the site of those tumors rather than elsewhere.

Selumetinib thwarts iodine resistance in thyroid cancer

The experimental drug selumetinib increased iodine uptake and retention in a subgroup of patients with radioiodine-resistant thyroid cancer.

Common genetic alteration in head and neck cancers may not be key to effective treatment

Although a large majority of head and neck cancers have a deregulation of the PI3K/AKT/mTOR pathway, recently published data indicates that deregulation of this pathway does not necessarily signify that the tumor is dependent on it for survival and progression.

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