Gynecologic Cancer

Vaginal Cuff Brachytherapy in Endometrial Cancer - A Technically Easy Treatment?

Vaginal Cuff Brachytherapy in Endometrial Cancer - A Technically Easy Treatment?

[Cancer Management and Research] This research examines vaginal cuff brachytherapy (VCB) in the postoperative treatment of high- to intermediate-risk endometrial cancer.

Niraparib Maintains Quality of Life in Recurrent Ovarian Cancer

Niraparib Maintains Quality of Life in Recurrent Ovarian Cancer

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Administering niraparib to patients with recurrent ovarian cancer after CR or PR to platinum-based chemotherapy may allow patients to continuously maintain QOL during treatment, reported researchers in presentation at ESMO 2017 Congress.

Sexual Dysfunction in Women With Cancer: A Review of Available Interventions

Sexual Dysfunction in Women With Cancer: A Review of Available Interventions

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Investigators conducted a review of available biologic and psychosocial interventions that address sexual dysfunction in women arising from cancer diagnosis and treatment.

Incidence of Invasive Cervical Cancer May Not Be Affected by HIV Status

Incidence of Invasive Cervical Cancer May Not Be Affected by HIV Status

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HIV infection may not have a contributory effect on the incidence of invasive cervical cancer (ICC) in women as they age.

Rates of Pregnancy Significantly Lower in Cancer Survivors Compared With General Population

Rates of Pregnancy Significantly Lower in Cancer Survivors Compared With General Population

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Girls and women aged 39 years and younger may be up to 38% less likely to achieve pregnancy after surviving cancer vs patients who have never had cancer.

Quality of Life in Ovarian Cancer Not Diminished by Olaparib

Quality of Life in Ovarian Cancer Not Diminished by Olaparib

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Change in FACT-O TOI score from baseline to 12 months did not differ significantly between maintenance olaparib and placebo.

Vaccine for Cervical Cancer Could Extend Survival in Relapsed Disease

Vaccine for Cervical Cancer Could Extend Survival in Relapsed Disease

Axalimogene filolisbac, an intravenous vaccine currently in clinical trials, could prevent often-fatal cervical cancer relapse.

Abdominal vs Laparoscopic Hysterectomy: Outcomes Similar for Endometrial Cancer

Abdominal vs Laparoscopic Hysterectomy: Outcomes Similar for Endometrial Cancer

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Disease-free survival and overall survival were similar in a study comparing total abdominal vs total laparoscopy hysterectomy approaches in women with stage I endometrial cancer.

Concurrent, Maintenance Therapy With Cediranib Maintains QOL in Ovarian Cancer

Concurrent, Maintenance Therapy With Cediranib Maintains QOL in Ovarian Cancer

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Quality of life was maintained in patients with ovarian cancer who received chemotherapy with concurrent cediranib then cediranib alone as maintenance therapy.

12 More Genetic Variants Found to Increase Risk for Ovarian Cancer

12 More Genetic Variants Found to Increase Risk for Ovarian Cancer

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A team of international researchers identified 12 new genetic variants that increase a woman's risk of developing ovarian cancer.

ASCO Issues Global Guidance for HPV Vaccination for Cervical Cancer Prevention

ASCO Issues Global Guidance for HPV Vaccination for Cervical Cancer Prevention

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ASCO offers global recommendations for HPV vaccination tailored to structural resource levels of regions.

Parental Self-persuasion in Low-Income Groups Improves HPV Vaccination Rates

Parental Self-persuasion in Low-Income Groups Improves HPV Vaccination Rates

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Self-persuasion is more effective than external persuasion for motivating low-income parents to vaccinate their children against HPV.

Quarterly Testing for Biomarker Improves Detection of Early-Stage Ovarian Cancer in High-Risk Women

Quarterly Testing for Biomarker Improves Detection of Early-Stage Ovarian Cancer in High-Risk Women

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A protocol of testing of CA125 levels quarterly with subsequent transvaginal ultrasound examination increased detection of early-stage ovarian cancer in women at high-risk for the disease.

Screening Increases Early Palliative Care, Reduces Aggressive EOL Measures

Screening Increases Early Palliative Care, Reduces Aggressive EOL Measures

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Universal screening of women with gynecologic malignancies for early palliative care decreased the use of aggressive measures at the end of life.

Endometrial Cancer Survivors in High-Poverty Areas Have Impaired Access to Self-Care Resources

Endometrial Cancer Survivors in High-Poverty Areas Have Impaired Access to Self-Care Resources

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Living in a high-poverty region is associated with lower access to obesity-related self-care resources.

Priority Symptoms Identified in Recurrent Ovarian Cancer

Priority Symptoms Identified in Recurrent Ovarian Cancer

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There are 18 core priority symptoms that should be routinely assessed in patients with recurrent ovarian cancer to provide higher quality of care.

Web-based Symptom Management Improves Symptom Controllability in Ovarian Cancer

Web-based Symptom Management Improves Symptom Controllability in Ovarian Cancer

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Nurse-guided and self-directed web-based symptom management interventions (WRITE Symptoms) improved symptom controllability among women with recurrent ovarian cancer.

Comorbidities May Predict Non-Home Discharge After Hysterectomy

Comorbidities May Predict Non-Home Discharge After Hysterectomy

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Presence of 1 risk factor or 2 or more risk factors is associated with non-home discharge after hysterectomy for gynecologic malignancy.

Some Quality Metrics Inconsistent With Long-Term Clinical Outcomes Goals

Some Quality Metrics Inconsistent With Long-Term Clinical Outcomes Goals

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Study finds that instituting a health system-wide quality metric, such as postoperative hospital readmission rate, may be inconsistent with long-term clinical outcomes goals.

Perioperative Pain Control Reduces Need for Postoperative Narcotics After Hysterectomy for Uterine Cancer

Perioperative Pain Control Reduces Need for Postoperative Narcotics After Hysterectomy for Uterine Cancer

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Preoperative intravenous acetaminophen plus local infiltration of LB during hysterectomy and surgical staging of uterine cancer may reduce the need for postoperative narcotics.

Perioperative Celecoxib Reduces Outpatient Narcotic Use After Hysterectomy

Perioperative Celecoxib Reduces Outpatient Narcotic Use After Hysterectomy

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Perioperative celecoxib use during hysterectomy may reduce the need for oral narcotics after hospital discharge.

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

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Use of chemotherapy or vaginal brachytherapy (VBT) may improve survival among patients with early-stage uterine papillary serous carcinoma.

High Rates of Persistent Opioid Use 6 Months After RT for Cervical Cancer

High Rates of Persistent Opioid Use 6 Months After RT for Cervical Cancer

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Nearly 3 in 10 cervical cancer survivors were still using opioids at 6 months after completing radiotherapy.

Nonadherence to Guidelines, Low-Volume Centers Linked to Lower Cervical Cancer Survival

Nonadherence to Guidelines, Low-Volume Centers Linked to Lower Cervical Cancer Survival

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Nonadherence to NCCN guideline treatment recommendations was strongly associated with decreased survival from early-stage cervical cancer.

HPV Vaccination Discussions Need to Focus on Education, Awareness

HPV Vaccination Discussions Need to Focus on Education, Awareness

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The top reasons for not initiating HPV vaccination are necessity, safety, and knowledge, rather than a lack of discussions on sexuality.

Ovarian Cancer: Distinct Clusters of Chemotherapy Nonresponders Identified

Ovarian Cancer: Distinct Clusters of Chemotherapy Nonresponders Identified

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A study that integrated genomic and clinical data identified 3 distinct clusters of patients with serous epithelial ovarian cancer who do not respond to chemotherapy.

Recovery Program After Laparotomy More Cost-Effective Than Usual Care

Recovery Program After Laparotomy More Cost-Effective Than Usual Care

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An enhanced recovery program is more cost-effective than usual care in patients undergoing primary cytoreductive surgery for ovarian cancer.

Rucaparib Active in Relapsed, Platinum-sensitive Ovarian Cancer

Rucaparib Active in Relapsed, Platinum-sensitive Ovarian Cancer

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Rucaparib was active with an acceptable safety profile in patients with relapsed, platinum-sensitive high-grade ovarian carcinoma with germline or somatic BRCA mutations.

Multidisciplinary Team Approach Reduces Cervical Cancer Treatment Delays in Low-Resource Areas

Multidisciplinary Team Approach Reduces Cervical Cancer Treatment Delays in Low-Resource Areas

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Multidisciplinary team approach reduces cervical cancer treatment delays in Botswana by 50%.

PI3K/mTOR Inhibitor Demonstrates Efficacy in Some Uterine Sarcomas

PI3K/mTOR Inhibitor Demonstrates Efficacy in Some Uterine Sarcomas

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A new generation dual PI3K/mTOR inhibitor shows promise in treating leiomyosarcomas with the protein P-S6S240.

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