Researchers identify tumor microenvironment of metastasis (TMEM) that allows breast cancer to metastasizeAugust 28, 2015
Using high-resolution imaging, scientists have gained a greater understanding of how a doorway in the blood vessel wall allows cancer cells to metastasize.
An international team has decoded the molecular characteristics of acute lymphoblastic leukemia (ALL), a cancer with some incurable subtypes.
DENVER, CO—The nurse navigator's role in cancer risk identification is three-fold. Despite the changes brought on by genetic/genomics, aspects of the nursing role are consistent with the essential competencies required of all professional nurses, according to a presentation at the 2015 Oncology Nurse Advisor Navigation Summit.
A new study indicates that the PD-1 protein pathway may niot be the only primary player in T cell exhaustion.
Genomic mapping of malignant pediatric adrenocortical tumors has revealed unprecedented details, not only of the aberrant genetic and chromosomal changes that drive the cancer, but the sequence of those changes that trigger it.
A new study links a well-known cell communication pathway called Notch to pilocytic astrocytoma (PA), one of the more common brain tumors found in children.
The molecular mail sent by multiple myeloma cells provides clues to how well patients with the disease are likely to respond to treatment, according to a study presented at ASH. The findings may ultimately guide doctors in deciding which therapies are best for individual patients with myeloma.
Molecular tests are poised to become a part of the treatment guidelines for prostate cancer. These tests provide information that extends beyond just identifying the type of cancer a patient has; they can also help narrow down treatment options to those that offer the best outcomes for patients.
A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas (TCGA) Research Network has identified markers of aggressive tumors, which could allow for improved targeted therapy.
Cytokine therapy enhances the activity of natural killer (NK) cells against tumors that lack the cell surface protein known as MHC class I, according to new research.
Evidence now suggests that human colon cells may become cancerous when they lose the ability to produce a specific hormone. For patients with colon cancer, replacing the hormone guanylin might prevent cancer development.
Blocking STAT3 in cells of the immune system actually leads to increased antitumor immunity, according to new research.
JAK inhibitors have been found to halt tumor growth in colorectal cancer with a certain genetic mutation, according to a new study.
Scientists have developed a tool to distinguish each breast cancer subtype, research that could improve treatments and targeting of treatments for the disease.
An international scientific collaboration has revealed clues about genetic alterations that may contribute to a rare form of kidney cancer, providing new insights not only into this rare cancer but other types as well.
All types of cancers appear to share a telltale signature of widespread changes to the epigenome.
Although mutations in a gene dubbed the "guardian of the genome" are recognized as being associated with more aggressive cancers, evidence suggests that the deleterious health effects of the mutated gene may in large part be due to other genetic abnormalities.
Researchers have identified a gene that contributes to the development of several childhood cancers, research that could lead to new strategies for targeting certain childhood cancers at a molecular level.
A protein present at high levels in more than half of all human cancers drives cell growth by blocking the expression of just a handful of genes involved in DNA packaging and cell death.
Brain tumors fly under the radar of the body's defense forces by coating their cells with extra amounts of a specific protein, according to new research.
The PALB2 gene is potentially one of the most important genes associated with breast cancer after the BRCA1/2 genes.
New research suggests that cancer would be more accurately diagnosed in 1 of every 10 patients if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated, and that this information, in turn, could lead to more appropriate treatments.
In a massive effort to catalog the molecular causes of stomach cancer, scientists have identified four subtypes of tumors based on shared mutations and other molecular abnormalities. They say the new classification promises to advance clinical research to develop improved therapies for the third-leading cancer killer worldwide.
In an analysis of small molecules called metabolites, a research team identified an enzyme key to applying the brakes on tumor growth.
The spreading of a cancerous tumor from one part of the body to another may occur through pure chance rather than through key genetic mutations, a new study has shown.
Scientists have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world's deadliest cancers.
A research team has discovered how two genes cause colorectal cancer cells to become resistant to treatments used against the disease.
A new study has identified three genetic changes in East Asian women linked to an increased risk of breast cancer.
For a rare form of cancer called thymoma, researchers have discovered a single gene defining the difference between a fast-growing tumor requiring aggressive treatment and a slow-growing tumor that does not require extensive therapy.
- New biomarker in breast and prostate cancer may help identify patients who will respond to taxanes
- What are immune checkpoints and how do they work?
- Among patients with myeloma undergoing chemo, high exercise compliance linked with reduced fatigue
- Efficacy and safety of docetaxel for advanced non-small-cell lung cancer: A meta-analysis of Phase III randomized controlled trials
- New combination treatment effective against cutaneous metastatic melanoma
- Religiousness and spirituality have a significant impact on cancer patients' overall health and outcomes
- Dietary intervention primes triple-negative breast cancer cells for targeted therapy
- Lung cancer patients who stop smoking live longer
- Study uses dog sledding to demonstrate benefits of adapted physical activities for children with cancer
- Review examines strategies for hospital room surface cleanliness
- Two-drug combination boosts survival in patients with metastatic prostate cancer
- Tell me about your prostate cancer symptoms ... Will most men talk or walk?
- Effects of glioblastoma treatments on healthy brain tissue continues after treatment is completed
- Aspirin reverses obesity cancer risk
- Patient-centered toolkit (PCTK) improves communication between patients, caregivers, and health care team
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