Single-agent nivolumab induced durable clinical responses with a manageable safety profile in previously treated patients with locally advanced or metastatic urothelial carcinoma.
Emulsifying Mycobacterium brumae in olive oil appeared promising for producing a robust immune response in preclinical tests. Recent research has indicated that M brumae is a safer alternative to BCG.
Researchers in Sweden have, for the first time, estimated the risk of developing various types of prostate cancer for men with brothers and/or fathers with the disease.
Functional status, a person's ability to perform normal activities of daily living, is associated with treatment choice for patients with prostate cancer.
Although overall risk for uterine cancer after risk-reducing salpingo-oophorectomy is not increased, the risk of serous/serous-like endometrial carcinoma is higher for BRCA1+ women.
US FDA granted accelerated approval to atezolizumab (TECENTRIQ), indicated for the treatment of locally advanced or metastatic UC in patients whose disease progressed during or following platinum-based chemotherapy, or in the neoadjuvant or adjuvant setting.
Although HPV vaccination is expected to decrease the cancer burden from HPV across all racial and ethnic groups, some disparities are expected to persist and widen if their causes are not addressed, including lack of access to screening, timely diagnoses, and treatment.
Patients with stage IIA testicular cancer gain a survival advantage from treatment with radiation therapy compared with chemotherapy.
Researchers believe arsenic exposure might contribute to higher-than-normal rates of bladder cancer in the region.
Pioglitazone use correlated with increased rates of bladder cancer across a large population. The risk of developing bladder cancer also increased with higher dose and longer use of the drug.
Older patients who undergo surgery to treat cancer are more likely to experience injuries and other health issues such as falling down, breaking bones, dehydration, bed sores, failure to thrive, and delirium. The risks are particularly notable in patients who undergo major abdominal surgery.
Recent developments in a gas chromatography tool might allow doctors to determine whether urologic cancers are present via a urine sample.
Mental health status prior to bladder cancer surgery may be associated with postoperative outcomes.
Researchers identified potential genetic alterations in penile cancer that could lead to targeted treatments for the disease. A complex landscape that could suggest clinical trials of targeted therapies was described in a recent report.
Taking muscle-building supplements significantly increases likelihood of developing testicular cancer.
The addition of chemotherapy after bladder cancer surgery lowered risk of death by approximately 30%, over surgery alone, according to a study that reviewed patient data.
Older white males with advanced bladder cancer are the most likely to commit suicide among patients with genitourinary cancers.
Risk factors for suicide include male gender, distant disease, increasing age, race/ethnicity.
Women with hematuria were less than half as likely as men with the same issue to be referred to a urologist for further tests, according to a new study.
A new study found that most women who undergo conservative surgery for vulvar cancer experience little to no long-term disruption to sexuality and body image.
The severity of acute urinary symptoms in patients who underwent radiotherapy for early prostate cancer can be predicted by using a modeling program together with the IPSS and dosage measure. These findings were presented at the 5th European Multidisciplinary Meeting on Urological Cancers.
Bladder cancer characterized by mutations of the STAG2 gene appears to be less likely to recur than bladder cancer with no such mutations, researchers have discovered.
Sulfasalazine, which is commonly prescribed to reduce diarrhea in patients with inflammatory bowel disease, does not reduce diarrhea in patients receiving radiation therapy for cancers in the pelvic area.
A gene that helps regulate bladder cancer growth and metastasis appears to be a promising target for detecting and monitoring the disease.
The American College of Physicians (ACP) recommends against prostate-specific antigen (PSA) screening for men older than age 69 and many others.
Risk of developing serious forms of urothelial carcinoma is significantly increased in smokers and leads to a higher likelihood of dying from the disease, especially for women.
A JCO study has found that Lynch syndrome carriers have an almost two-fold cumulative chance of prostate cancer at ages 60 and 80 years.
Levels of three serum proteins are much higher in kidney cancer patients, lending a highly accurate diagnosis.
Women with Lynch syndrome and endometrial cancer have elevated risks for several other cancers, including breast, bladder, and kidney cancers.
Although low-risk bladder cancer rarely escalates to muscle invasion, it is associated with an increased risk of disease-specific mortality compared with the general population.
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