Genitourinary Cancer

How We Developed a New Protocol for Treatment of Urethral Carcinoma

How We Developed a New Protocol for Treatment of Urethral Carcinoma

Faced with a harsh treatment option, a patient with genitourinary cancer helps create a treatment plan that preserves his self-image.

Nivolumab Monotherapy Active in Recurrent Metastatic Urothelial Carcinoma

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Single-agent nivolumab induced durable clinical responses with a manageable safety profile in previously treated patients with locally advanced or metastatic urothelial carcinoma.

Mycobacteria Treatment for Bladder Cancer More Effective With Emulsification in Olive Oil

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Emulsifying Mycobacterium brumae in olive oil appeared promising for producing a robust immune response in preclinical tests. Recent research has indicated that M brumae is a safer alternative to BCG.

Researchers Estimate Familial Prostate Cancer Risk

Researchers Estimate Familial Prostate Cancer Risk

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Researchers in Sweden have, for the first time, estimated the risk of developing various types of prostate cancer for men with brothers and/or fathers with the disease.

Functional Status Linked to Treatment Choice for Prostate Cancer

Functional Status Linked to Treatment Choice for Prostate Cancer

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Functional status, a person's ability to perform normal activities of daily living, is associated with treatment choice for patients with prostate cancer.

<i>BRCA1</i> Mutations May Raise Risk of Serous and Serous-Like Uterine Cancer

BRCA1 Mutations May Raise Risk of Serous and Serous-Like Uterine Cancer

Although overall risk for uterine cancer after risk-reducing salpingo-oophorectomy is not increased, the risk of serous/serous-like endometrial carcinoma is higher for BRCA1+ women.

Atezolizumab Approved for Locally Advanced or Metastatic Urothelial Carcinoma

Atezolizumab Approved for Locally Advanced or Metastatic Urothelial Carcinoma

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US FDA granted accelerated approval to atezolizumab (TECENTRIQ), indicated for the treatment of locally advanced or metastatic UC in patients whose disease progressed during or following platinum-based chemotherapy, or in the neoadjuvant or adjuvant setting.

More Than HPV Vaccine Uptake Is Needed to Reduce the Burden of HPV-associated Cancers

More Than HPV Vaccine Uptake Is Needed to Reduce the Burden of HPV-associated Cancers

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Although HPV vaccination is expected to decrease the cancer burden from HPV across all racial and ethnic groups, some disparities are expected to persist and widen if their causes are not addressed, including lack of access to screening, timely diagnoses, and treatment.

Radiation Therapy Better Than Chemotherapy for Stage IIA Testicular Cancer

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Patients with stage IIA testicular cancer gain a survival advantage from treatment with radiation therapy compared with chemotherapy.

Well Water a Suspected Cause of Bladder Cancer in New England

Well Water a Suspected Cause of Bladder Cancer in New England

Researchers believe arsenic exposure might contribute to higher-than-normal rates of bladder cancer in the region.

Risk of Bladder Cancer Higher for Patients Taking a Specific Diabetes Medication

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Pioglitazone use correlated with increased rates of bladder cancer across a large population. The risk of developing bladder cancer also increased with higher dose and longer use of the drug.

Certain Cancer Surgeries Increase Risks for Injuries and Other Health Concerns in Older Patients

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Older patients who undergo surgery to treat cancer are more likely to experience injuries and other health issues such as falling down, breaking bones, dehydration, bed sores, failure to thrive, and delirium. The risks are particularly notable in patients who undergo major abdominal surgery.

Diagnostic Tool Can Smell Bladder Cancer or Prostate Cancer in a Urine Sample

Diagnostic Tool Can Smell Bladder Cancer or Prostate Cancer in a Urine Sample

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Recent developments in a gas chromatography tool might allow doctors to determine whether urologic cancers are present via a urine sample.

Mental Health Status May Impact Bladder Cancer Surgery Outcomes

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Mental health status prior to bladder cancer surgery may be associated with postoperative outcomes.

New Research Takes a First Step Toward Targeted Therapy for Penile Cancer

New Research Takes a First Step Toward Targeted Therapy for Penile Cancer

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Researchers identified potential genetic alterations in penile cancer that could lead to targeted treatments for the disease. A complex landscape that could suggest clinical trials of targeted therapies was described in a recent report.

Muscle-building supplements may be associated with testicular cancer

Muscle-building supplements may be associated with testicular cancer

Taking muscle-building supplements significantly increases likelihood of developing testicular cancer.

Chemotherapy after bladder cancer surgery improves survival

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The addition of chemotherapy after bladder cancer surgery lowered risk of death by approximately 30%, over surgery alone, according to a study that reviewed patient data.

Older white males with advanced bladder cancer more likely to commit suicide

Older white males with advanced bladder cancer more likely to commit suicide

Older white males with advanced bladder cancer are the most likely to commit suicide among patients with genitourinary cancers.

Suicide deemed public health concern in those with genitourinary cancers

Suicide deemed public health concern in those with genitourinary cancers

Risk factors for suicide include male gender, distant disease, increasing age, race/ethnicity.

Fewer women than men are referred to urologists for suspicion of bladder cancer

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Women with hematuria were less than half as likely as men with the same issue to be referred to a urologist for further tests, according to a new study.

Body image and sex life stay healthy for most women undergoing vulvar cancer surgery

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A new study found that most women who undergo conservative surgery for vulvar cancer experience little to no long-term disruption to sexuality and body image.

Clinical predictors of acute urinary symptoms after prostate radiotherapy

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The severity of acute urinary symptoms in patients who underwent radiotherapy for early prostate cancer can be predicted by using a modeling program together with the IPSS and dosage measure. These findings were presented at the 5th European Multidisciplinary Meeting on Urological Cancers.

Gene mutation linked with low recurrence risk in bladder cancer

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Bladder cancer characterized by mutations of the STAG2 gene appears to be less likely to recur than bladder cancer with no such mutations, researchers have discovered.

Drug fails to reduce diarrhea in patients receiving radiation therapy

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Sulfasalazine, which is commonly prescribed to reduce diarrhea in patients with inflammatory bowel disease, does not reduce diarrhea in patients receiving radiation therapy for cancers in the pelvic area.

MDA-9/syntenin gene may help detect, manage bladder cancer

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A gene that helps regulate bladder cancer growth and metastasis appears to be a promising target for detecting and monitoring the disease.

ACP: Harms of PSA testing outweigh benefits for many men

The American College of Physicians (ACP) recommends against prostate-specific antigen (PSA) screening for men older than age 69 and many others.

Urothelial cancer prognosis worse for smokers, particularly women

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Risk of developing serious forms of urothelial carcinoma is significantly increased in smokers and leads to a higher likelihood of dying from the disease, especially for women.

Carriers of Lynch syndrome have two-fold increased risk of prostate cancer

Carriers of Lynch syndrome have two-fold increased risk of prostate cancer

A JCO study has found that Lynch syndrome carriers have an almost two-fold cumulative chance of prostate cancer at ages 60 and 80 years.

Three biomarkers can detect kidney cancer with high accuracy

Three biomarkers can detect kidney cancer with high accuracy

Levels of three serum proteins are much higher in kidney cancer patients, lending a highly accurate diagnosis.

Lynch-related endometrial cancer raises risk of other cancers

Women with Lynch syndrome and endometrial cancer have elevated risks for several other cancers, including breast, bladder, and kidney cancers.

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