General Oncology

Cost of Care Significantly Increased With Carcinoid Syndrome in NETs

Cost of Care Significantly Increased With Carcinoid Syndrome in NETs

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Development of carcinoid syndrome has a profound effect on cost of care for patients with neuroendocrine tumors (NETs).

Efficacy of Octreotide LAR, Lanreotide in Management of Carcinoid Tumors

Efficacy of Octreotide LAR, Lanreotide in Management of Carcinoid Tumors

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Benefits of long-acting, repeatable octreotide and lanreotide in neuroendocrine tumors, formerly known as carcinoid tumors, are similar.

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy

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Bevacizumab-awwb is a recombinant IgG1 monoclonal antibody that works by binding to vascular endothelial growth factor (VEGF) and inhibits angiogenesis.

No Benefit to Extensive Cancer Screening in Unprovoked Venous Thromboembolism

No Benefit to Extensive Cancer Screening in Unprovoked Venous Thromboembolism

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Although unprovoked VTE may be a sign of occult cancer, results of a meta-analysis showed no benefit to extensive cancer screening in these patients.

FDA Approves Supplemental Indication for Lanreotide Depot for Carcinoid Syndrome

FDA Approves Supplemental Indication for Lanreotide Depot for Carcinoid Syndrome

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Patients who receieved lanreotide depot had a significantly lower percentage of days when rescue octreotide was used compared with placebo.

Median Cost of Cancer Drug Development is Approximately $648 Million

Median Cost of Cancer Drug Development is Approximately $648 Million

Total revenue from sales of 10 drugs was 67.0 billion, with total RD spending of 7.2 billion, researchers found.

Cannabis Reduces Response Rate to Immunotherapy for Cancer

Cannabis Reduces Response Rate to Immunotherapy for Cancer

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Investigators report that administering cannabis to patients with cancer undergoing immunotherapy was found to lower the response rate to therapy but had no effect on PFS or OS, in an oral presentation at ESMO 2017 Congress.

Prevalence of Aggressive Cancer Care at End of Life Remains Unchanged

Prevalence of Aggressive Cancer Care at End of Life Remains Unchanged

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Researchers reported trends of aggressiveness of cancer care near the end of life (ACCEoL) have remained unchanged in adult patients despite increasing resources for integrated palliative care in a presentation at ESMO 2017 Congress.

Impact of Distress on Adherence to Cancer Screening Recommendations

Impact of Distress on Adherence to Cancer Screening Recommendations

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Most studies focus on false-positive results and follow-ups. In this study, researchers sought to determine distress levels at the time of screening and its potential impact on adherence to screening recommendations.

Breakthrough Cancer Pain Managed Effectively With Fentanyl Buccal Tablets

Breakthrough Cancer Pain Managed Effectively With Fentanyl Buccal Tablets

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This prospective, noninterventional trial evaluated the response of 276 patients to FBT from 64 pain and oncology clinics

Cause of Superior Vena Cava Syndrome in Cancer Determines Prognosis

Cause of Superior Vena Cava Syndrome in Cancer Determines Prognosis

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Prognosis for cancer patients with superior vena cava syndrome is highly associated with the underlying cause of the syndrome.

Hyponatremia May Lead to Worse Symptom Severity, Frequency in Cancer

Hyponatremia May Lead to Worse Symptom Severity, Frequency in Cancer

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Patients with cancer who develop hyponatremia suffer from more symptoms with greater severity than normonatremic patients; however, no significant association was found between in-hospital mortality or length of hospital stay and hyponatremia.

Affect of Daratumumab on Laboratory Blood Test Results

Affect of Daratumumab on Laboratory Blood Test Results

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Do monoclonal antibodies other than daratumumab cause false positives in the blood antibody screen and crossmatch obtained prior to a transfusion?

Early Recognition of Checkpoint Inhibitor-Related Pneumonitis Improves Outcomes

Early Recognition of Checkpoint Inhibitor-Related Pneumonitis Improves Outcomes

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As the use of checkpoint inhibitors increases in many types of cancer, oncology nurses need to learn to recognize the signs and symptoms of pneumonitis, a rare but life-threatening adverse effect of these agents.

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

Risk of Some Cancers Higher in Women With a History of Periodontal Disease

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A study on a cohort of women enrolled in the WHI-OS shows that those with a history of periodontal disease had a higher risk for developing some cancers.

Risk of Arterial Thromboembolism Greater With First-Time Cancer

Risk of Arterial Thromboembolism Greater With First-Time Cancer

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An increase in risk for arterial thromboembolism was correlated with cancer stage and varied by cancer type.

Cancer Patient Caregivers Have Increased Burden With Assessment Dissonance

Cancer Patient Caregivers Have Increased Burden With Assessment Dissonance

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There is an increased burden on caregivers to not only assist with IADLs but also to assess patient conditions and provide health care information.

Sexual Dysfunction in Women With Cancer: A Review of Available Interventions

Sexual Dysfunction in Women With Cancer: A Review of Available Interventions

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Investigators conducted a review of available biologic and psychosocial interventions that address sexual dysfunction in women arising from cancer diagnosis and treatment.

Insured Patients with Cancer May Experience Financial Distress

Insured Patients with Cancer May Experience Financial Distress

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Cancer treatment is far costlier than expected, even for patients with cancer who have health insurance coverage, with being underinsured causing in the most distress for patients.

Optimal Treatment Regimens for Oldest Patients Is an Emerging Challenge for Radiation Oncology

Optimal Treatment Regimens for Oldest Patients Is an Emerging Challenge for Radiation Oncology

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A look at the significant influence of age-adjusted prognoses and treatment priorities for radiation therapy in the oldest patients with cancer.

Opioid Use Higher Among Cancer Survivors, Even After Long-Term Survivorship

Opioid Use Higher Among Cancer Survivors, Even After Long-Term Survivorship

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Rates of opioid prescription use is higher among patients with cancer compared with patients who have never had cancer, even after survivorship.

To Better Serve Patients With Cancer, Navigators Need Better Systems

To Better Serve Patients With Cancer, Navigators Need Better Systems

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A navigator offers her take on how the ideal EHR system could unify the oncology care team toward the common goal of optimal patient outcomes.

ASCO Updates Guidelines for Antiemetic Therapy in Adult, Pediatric Patients Receiving Chemotherapy

ASCO Updates Guidelines for Antiemetic Therapy in Adult, Pediatric Patients Receiving Chemotherapy

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The American Society of Clinical Oncology (ASCO) convened a panel of experts to update its clinical guidelines for antiemetic therapy in patients receiving chemotherapy. A notable change is the addition of olanzapine in emetic regimens for adult patients.

Lack of Training Associated With Cancer Patient Caregiver Burden

Lack of Training Associated With Cancer Patient Caregiver Burden

Correlation between training and caregiver burden was partially mediated by confidence, researchers found.

Risk of Certain Cancers Found Lower in Nonsmokers Who Consume Coffee

Risk of Certain Cancers Found Lower in Nonsmokers Who Consume Coffee

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Researchers investigated the effect of drinking coffee on risk of several cancers, and in addition, the coffee drinkers were stratified by smoking status.

Chemotherapy-associated Paronychia Treated With 2% Povidone-iodine: A Series of Cases

Chemotherapy-associated Paronychia Treated With 2% Povidone-iodine: A Series of Cases

[Cancer Management and Research] This research examines cases of chemotherapy-induced nail changes in individuals treated with taxanes and EGFR inhibitors.

COX-2 Inhibitors Can Improve Response to Immunotherapy of Some Cancer Tumors

COX-2 Inhibitors Can Improve Response to Immunotherapy of Some Cancer Tumors

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Tumors that express the protein IDO1 constitutively respond to the COX-2 inhibitor celecoxib and have increased infiltration of certain T-cell subsets, making them more responsive to anti-PD1 treatment.

Palliative Cancer Care Should Focus on Symptoms, Not Diagnoses

Palliative Cancer Care Should Focus on Symptoms, Not Diagnoses

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Results of a cross-sectional study determined that symptoms and care needs dictate palliative care needs of patients with cancer.

Treating the Other "Patient": Depressive Symptoms Are Predictive of Declining Physical Health in Caregivers

Treating the Other "Patient": Depressive Symptoms Are Predictive of Declining Physical Health in Caregivers

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The person with cancer is not always the oncology nurse's only patient. Caregivers should be assessed for depressive symptoms, which can indicate declining physical health in the caregiver, and receive appropriate treatment.

Opioids Overprescribed in Patients Undergoing Surgery

Opioids Overprescribed in Patients Undergoing Surgery

A significant variation in opioid prescribing practices was observed for each of 25 common elective procedures.

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