Daily Dose Thresholds for Antipsychotics

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DAILY DOSE THRESHOLDS: ANTIPSYCHOTICS
Generic Brand Usual Max
Oral Daily
Dose
Max Daily Dose to
Manage Behavioral 
Symptoms Related to
Dementing Illnesses
FIRST GENERATION
chlorpromazine 800mg  75mg
fluphenazine  40mg   4mg
haloperidol 100mg   2mg
loxapine Adasuve  10mg
Loxitane 250mg  10mg
perphenazine  64mg   8mg
pimozide Orap  10mg   *
prochlorperazine 150mg   *
thioridazine 800mg  75mg
thiothixene Navane  60mg   7mg
trifluoperazine  40mg   8mg
ATYPICAL ANTIPSYCHOTICS
aripiprazole Abilify  30mg  10mg
asenapine Saphris  20mg   *
brexpiprazole Rexulti   4mg   *
clozapine Clozaril 900mg  50mg
iloperidone Fanapt  24mg   *
olanzapine Zyprexa  20mg 7.5mg
paliperidone Invega  12mg   *
quetiapine Seroquel 800mg 150mg
risperidone Risperdal  16mg   2mg
ziprasidone Geodon 160mg   *

* Not customarily used for the treatment of behavioral symptoms.

REFERENCES

Adapted from the CMS State Operations Manual: Appendix PP - Guidance to Surveyors for Long Term Care Facilities.
Available at: cms.hhs.gov/manuals/Downloads/
som107ap_pp_guidelines_ltcf.pdf
. Accessed 9/2010.

(Rev. 9/2015)

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