Two infants with advanced acute lymphoblastic leukemia (ALL) achieved full remission following gene therapy involving modified autologous CAR-T cells.
[Clinical Medicine Insights] In this case study, a 63-year-old man with metastatic castration-resistant prostate cancer (CRPC) was successfully treated for two years with in situ gene therapy using an adenovirus vector carrying the human REIC/Dkk‑3 gene.
Scientists have shown that DNA origami can be used for the targeted delivery of cancer drugs to tumor cells in mice.
Adding to the picture of what prompts breast cancer to form, researchers have found that distant estrogen response elements can act independently of oncogenes to spur tumor development.
Cellular therapy and gene therapy have been successfully combined in a mouse model to develop a viable treatment strategy for breast cancer that has spread to a patient's brain.
A gene that helps regulate bladder cancer growth and metastasis appears to be a promising target for detecting and monitoring the disease.
A small study showed the safety of using gene therapy in the salivary gland to repair damage caused by radiation for head and neck cancer.
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