Gene Therapy

Ad-REIC Gene Therapy: Promising Results in a Patient with Metastatic CRPC Following Chemotherapy

Ad-REIC Gene Therapy: Promising Results in a Patient with Metastatic CRPC Following Chemotherapy

[Clinical Medicine Insights] In this case study, a 63-year-old man with metastatic castration-resistant prostate cancer (CRPC) was successfully treated for two years with in situ gene therapy using an adenovirus vector carrying the human REIC/Dkk‑3 gene.

DNA origami can deliver targeted cancer drugs

DNA origami can deliver targeted cancer drugs

Scientists have shown that DNA origami can be used for the targeted delivery of cancer drugs to tumor cells in mice.

Estrogen enhancers tied to aggressive breast cancer

Estrogen enhancers tied to aggressive breast cancer

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Adding to the picture of what prompts breast cancer to form, researchers have found that distant estrogen response elements can act independently of oncogenes to spur tumor development.

New therapy strategy for breast cancer that has spread to the brain

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Cellular therapy and gene therapy have been successfully combined in a mouse model to develop a viable treatment strategy for breast cancer that has spread to a patient's brain.

MDA-9/syntenin gene may help detect, manage bladder cancer

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A gene that helps regulate bladder cancer growth and metastasis appears to be a promising target for detecting and monitoring the disease.

Gene therapy safely increased saliva flow after head and neck cancer

A small study showed the safety of using gene therapy in the salivary gland to repair damage caused by radiation for head and neck cancer.

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