ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

GATTEX
Colorectal disorders
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

GATTEX Rx

Generic Name and Formulations:
Teduglutide 5mg; per vial; lyophilized pwd for SC inj after reconstitution.

Company:
Shire US, Inc.

Therapeutic Use:

Indications for GATTEX:

Treatment of adult patients with short bowel syndrome (SBS) who are dependent on parenteral support.

Adult:

Administer by SC inj only; alternate sites between 1 of the 4 quadrants of the abdomen, or into alternating thighs or arms. 0.05mg/kg once daily. Do not take 2 doses on the same day. Moderate-to-severe renal impairment (CrCl <50mL/min) and ESRD: reduce dose by 50%.

Children:

Not established.

Warnings/Precautions:

Risk of neoplastic growth acceleration. Discontinue in active GI malignancy (eg, GI tract, hepatobiliary, pancreatic), colorectal or small bowel cancer. Perform colonoscopy with removal of polyps within 6 months before starting; repeat at end of 1yr therapy and every 5yrs or more as needed. Temporarily discontinue if intestinal or stomal obstruction develops; may restart if resolves. Monitor for biliary and pancreatic disease; assess bilirubin, alkaline phosphatase, lipase, amylase within 6 months before starting and at least every 6 months during treatment, or more if needed. Risk of fluid overload; if occurs, adjust parenteral support and reassess treatment (esp. in underlying cardiovascular disease). Reevaluate treatment if significant cardiac deterioration develops. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Concomitant oral drugs requiring titration or with a narrow therapeutic index (eg, benzodiazepines, phenothiazines): may require dose adjustment and monitor.

Pharmacological Class:

Glucagon-like peptide-2 (GLP-2) analogue.

Adverse Reactions:

Abdominal pain, inj site reactions, nausea, headaches, abdominal distension, upper respiratory tract infection, vomiting, fluid overload.

REMS:

YES

How Supplied:

One-vial kit, 30-vial kit—1 (single-use vials w. supplies)

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs