Clinical trials show pembrolizumab active against mucosal melanoma, extends survival in bladder cancer.
An investigation into whether onset or worsening of diabetes causes pancreatic cancer or vice versa was presented at the 2017 European Cancer Congress.
Research presented at the 2017 European Cancer Congress describes the potential of a noninvasive diagnostic test for esophageal and gastric cancers that measures chemicals in the breath.
Chemotherapy may be overused among young and middle-aged adults with colon cancer, with the addition of adjuvant chemotherapy not resulting in a matched survival benefit.
PDX1 appears to have distinct roles at different stages of pancreatic cancer development.
Researchers conduct a retrospective cohort study of histologically diagnosed gastrointestinal stromal tumors in the Surveillance, Epidemiology, and End Results (SEER) database.
Researchers have found that hepatitis C virus infection is associated with an elevated risk for developing bile duct cancers and diffuse large B-cell lymphoma.
In a phase 3 trial, researchers determined if weekly nab-paclitaxel was noninferior to weekly solvent-based paclitaxel with respect to overall survival in patients requiring second-line treatment for advanced gastric cancer.
Findings are presented from an open-label NETTER-1 clinical trial evaluating the efficacy and safety of 177Lu-Dotatate in patients with advanced midgut neuroendocrine tumors who have experienced disease progression during first-line treatment with a somatostatin analogue.
Drug-drug interaction between capecitabine and common heartburn medications has a negative effect on progression-free survival and overall survival in patients with GI cancer.
Given the frequency of gene mutations in patients with early-onset CRC, genetic counseling and testing could be considered for this population.
Adding the mesenchymal-epithelial transition (MET) antibody onartuzumab did not significantly improve clinical outcomes.
Survey data from patients receiving care at Boston Medical Center who were navigated for colonoscopy screening illustrates how patients value the services of oncology patient navigators.
A possible association between moderate to heavy alcohol consumption has been shown in previous studies. In this study, investigators examined the relationship between alcohol consumption and colorectal cancer survival remains unclear.
Smoking-attributable cancer mortality estimates have not been established by state; therefore, in this study, the proportion of cancer deaths among persons 35 years and older related to cigarette smoking in 2014 was calculated for each state and DC.
Novel preparation formulation is as effective and safe as current colon prep for colonoscopy. Plus, study participants gave the prep experience a high satisfaction rating.
Because gastric acid suppressants, such as proton pump inhibitors, affect the absorption of some oral cancer medications, researchers sought to determine if proton pump inhibitors impair capecitabine efficacy.
A review of adverse effects and recommended management for 3 kinase inhibitors indicated for the treatment of gastrointestinal cancers.
Adding rolapitant to a 5-HT3 receptor antagonist and dexamethasone significantly improved the prevention of CINV in patients with GI and CRC cancers receiving highly or moderately emetogenic chemotherapy.
Applying evolutionary theory improves the accuracy of predicting in which patients Barrett's esophagus will progress to esophageal adenocarcinoma.
Lifestyle and dietary measures for preventing colorectal cancer are extensively studied; however, in this study, researchers looked at a dietary measure that improved survival for patients after diagnosis.
Poor compliance to NCCN guidelines for adjuvant chemotherapy appears to be associated with poorer overall survival.
Research indicates that metformin can confer improved survival for patients with colorectal cancer that also have diabetes.
Research findings reveal the mechanism by which obesity increases inflammation and desmoplasia in the most frequent type of pancreatic cancer, using mouse models and human tissue samples.
Systematic Palliative Care Provides Greater Improvement in Quality of Life for Patients with Pancreatic CancerJuly 29, 2016
Quality of life is significantly improved for patients with pancreatic cancer when systematic palliative care is administered vs on-demand palliative care.
Genetic biomarkers from tumor DNA circulating in the bloodstream could indicate the risk for recurrence of colorectal cancer and the efficacy of chemotherapy after surgery.
The multikinase inhibitor regorafenib significantly improved overall survival rates compared to placebo in patients with hepatocellular carcinoma, according to data from the phase 3 RESORCE trial.
Using a computer algorithm to scan images of the esophagus for signs of early esophageal cancer is nearly as accurate as top specialists.
Adjuvant chemotherapy is associated with improved overall survival in patients with stage II colon cancer regardless of treatment regimen, patient age, or high-risk pathologic risk features.
The proportion of older patients with comorbidities receiving treatment for metastatic colorectal cancer (mCRC) has increased over the last 2 decades despite the overall percentage of older adults being treated remaining low.
- Cholesterol-Lowering Drugs May Prevent Breast Cancer Recurrence
- BBD Regimen Efficacious as First-line Therapy for Myeloma
- Idelalisib Increases Progression-Free Survival in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia
- Trends in Behaviors, Medical Practice Indicate Mortality From Melanoma Will Decline
- Pembrolizumab Active Against Rare Melanoma, Extends Survival in Bladder Cancer
- Survivors Reporting Chronic Neuropathic Pain Struggle to Retain Jobs
- Timing of Chemotherapy Infusion Affects Inflammatory Response to Chemotherapy
- Postoperative Gemcitabine Plus Capecitabine: A New Standard of Care for Pancreatic Cancer
- Blood-Forming Stem Cell Transplants (Fact Sheet)
- Nut Consumption Inversely Associated With Lung Cancer Risk
- Best Approach to Infection and Tumor Treatment: Contain or Eliminate?
- Decipher Genomic Classifier Prognostic for Distant Prostate Metastasis
- GUCS 2017: Adjuvant Trials in Post-radical Prostatectomy Prostate Cancer Feasible
- Annual Screening of High-Risk Smokers Only More Cost-effective Than Current Methods
- Blood Test Predicts Stem Cell Transplant Success in Myelodysplastic Syndrome
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