Gastrointestinal Cancer News & Features

EGFR antagonists compared in colorectal cancer trial

Phase 3 trial evaluating Vectibix vs. Erbitux for the treatment of chemo-refractory metastatic colorectal cancer meets its primary endpoint for overall survival.

Axitinib (Inlyta)

Axitinib (Inlyta)

Axitinib is a multitargeted TKI indicated for the treatment of advanced RCC after failure of one prior systemic therapy.

Comprehensive talks with primary care providers up CRC screening

Comprehensive talks with primary care providers up CRC screening

Having more comprehensive discussions about colorectal cancer screening with primary care providers (PCPs) is associated with increased odds of screening.

Female smokers susceptible to proximal colon cancer

Female smokers susceptible to proximal colon cancer

Female smokers have a significantly increased risk of colon cancer, particularly for proximal colon cancer, compared to male smokers.

Full Clinical Benefits of Regorafenib in mCRC Attainable When AEs Are Proactively Managed

Adverse events associated with regorafenib are manageable with a proactive strategy that includes prophylactic treatment and education for the patient, caregiver, and healthcare provider, research presented at the ONS 38th Annual Congress has shown.

Cetuximab enables liver metastasis surgery in colorectal cancer

Combining cetuximab (Erbitux) with standard therapy improved the resectability of previously inoperable liver metastases of colorectal cancer.

Anesthesia raises risk of colonoscopy complications

Although the absolute risk is low, use of anesthesia for colonoscopy is associated with a somewhat higher frequency of complications.

Certain geriatric factors can predict how patients with mCRC will tolerate chemotherapy

Certain geriatric factors can predict how patients with mCRC will tolerate chemotherapy

For elderly patients with metastatic colorectal cancer, certain geriatric scores were predictive of severe toxicity or unexpected hospitalization after fluorouracil-based chemotherapy with or without irinotecan.

Surgery plus radiation boosts survival in metastatic gastric cancer

Persons with metastatic gastric cancer who had both surgery and radiation lived longer than patients who underwent one or neither treatment.

Benchmarks for adenoma detection may be too low

A recent study uncovered adenoma detection rates significantly higher than those set in national guidelines.

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