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FURADANTIN
Bacterial infections
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Drug Name:

FURADANTIN Rx

Generic Name and Formulations:
Nitrofurantoin 25mg/5mL; susp.

Company:
Shionogi, Inc.

Therapeutic Use:

Indications for FURADANTIN:

Susceptible UTIs.

Adult:

Take with food. 50–100mg 4 times daily. Suppressive therapy: 50–100mg once daily at bedtime may suffice.

Children:

Take with food. <1month: contraindicated. ≥1month: 5–7mg/kg per day in 4 divided doses. Suppressive therapy: 1mg/kg per day in 1–2 divided doses may suffice.

Contraindications:

Renal impairment (CrCl <60mL/min or significantly elevated serum creatinine), anuria, oliguria. Neonates. Labor & delivery. Pregnancy at term. History of cholestatic jaundice or hepatic dysfunction.

Warnings/Precautions:

Not for treating pyelonephritis or perinephric abscesses. Discontinue if pulmonary or hepatic disorders, hemolysis, or peripheral neuropathy occurs. Renal insufficiency. G6PD or Vit. B deficiency. Anemia. Diabetes. Electrolyte imbalance. Debilitated. Monitor renal and pulmonary function in long-term use. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Avoid magnesium trisilicate. Antagonized by, and increased toxicity with uricosurics (eg, probenecid). May cause false (+) glucose test with Benedict's or Fehling's solution.

Pharmacological Class:

Antibiotic.

Adverse Reactions:

Nausea, emesis, anorexia, dizziness, headache, pulmonary or hematological disorders (esp. in long-term use), peripheral neuropathy, allergic reactions, C. difficile-associated diarrhea; rare: hepatic dysfunction, exfoliative dermatitis, Stevens-Johnson syndrome, optic neuritis, methemoglobinemia.

How Supplied:

Susp—230mL

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