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Fluphenazine Concentrate
Psychosis
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Drug Name:

Fluphenazine Concentrate Rx

Generic Name and Formulations:
Fluphenazine HCl 5mg/mL; alcohol 14%. Dilute just before administration.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Fluphenazine Concentrate:

Psychosis.

Adult:

Initially: 2.5–10mg daily in 3–4 divided doses; max 40mg daily.

Children:

Not recommended.

Elderly:

Initially 1–2.5mg daily in 3–4 divided doses; max 40mg daily.

Contraindications:

Coma. CNS or bone marrow depression. Liver disease. Subcortical brain damage. Blood dyscrasias.

Warnings/Precautions:

Cardiovascular or renal disease. Pheochromocytoma. Seizures. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Gradually reduce to lowest effective maintenance dose. Monitor blood, liver, renal, and ocular function. Mental retardation. Surgery. Pregnancy. Nursing mothers.

Interactions:

Potentiates anticholinergics, CNS depression with alcohol and other CNS depressants; both drugs with propranolol. Antagonized by anticholinergics. Decreased guanethidine effects. May cause false (+) pregnancy test.

See Also:

Fluphenazine

Fluphenazine Elixir

Fluphenazine Inj

Fluphenazine Decanoate Inj

Pharmacological Class:

Piperazine phenothiazine.

Adverse Reactions:

Drowsiness, anticholinergic and other autonomic effects, insomnia, restlessness, rash, photosensitivity, tardive dyskinesia, blood dyscrasias, jaundice, pneumonia, hypertension, retinopathy, lowered seizure threshold, extrapyramidal reactions, neuroleptic malignant syndrome, weight changes, endocrine effects.

Note:

Formerly known under the brand names Prolixin (tabs, concentrate, elixir, inj); Permitil (tabs, concentrate); Prolixin Decanoate (decanoate inj).

How Supplied:

Contact supplier.

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