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FIRMAGON
Prostate and other male cancers
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Drug Name:

FIRMAGON Rx

Generic Name and Formulations:
Degarelix 80mg/vial, 120mg/vial; pwd for SC inj after reconstitution.

Company:
Ferring Pharmaceuticals, Inc.

Therapeutic Use:

Indications for FIRMAGON:

Advanced prostate cancer.

Adult:

Give by SC inj in abdomen once every 28 days; avoid waist and rib areas. Two 120mg injections once, then one 80mg inj once every 28 days.

Children:

Not established.

Contraindications:

Pregnancy (Cat.X).

Warnings/Precautions:

Congenital long QT syndrome. CHF. Correct electrolyte abnormalities. Monitor electrolytes and ECG periodically. Monitor serum PSA. Discontinue if serious hypersensitivity reaction occurs; do not rechallenge. Moderate or severe renal impairment (CrCl <50mL/min). Severe hepatic impairment. Nursing mothers: not recommended.

Interactions:

Caution with concomitant drugs known to prolong the QT interval.

Pharmacological Class:

GnRH antagonist.

Adverse Reactions:

Inj site reactions (eg, pain, erythema, swelling, induration), hot flashes, increased weight, fatigue, increased transaminases, increased gamma-glutamyltransferase; QT prolongation.

How Supplied:

Treatment Initiation pack (120mg/vial)—2 (w. supplies); Treatment Maintenance pack (80mg/vial)—1 (w. supplies)

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