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FIRAZYR
Hereditary angioedema
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Drug Name:

FIRAZYR Rx

Generic Name and Formulations:
Icatibant 10mg/mL; soln for SC inj; preservative-free.

Company:
Shire US, Inc.

Therapeutic Use:

Indications for FIRAZYR:

Treatment of acute attacks of hereditary angioedema (HAE).

Adult:

≥18yrs: 30mg SC in abdominal area; may give additional doses at intervals of at least 6 hours if response inadequate or symptoms recur. Max 3 doses/24hrs.

Children:

<18yrs: not recommended.

Warnings/Precautions:

Advise patients to seek medical attention after treating laryngeal attack given the potential for airway obstruction. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers.

Interactions:

May attenuate the antihypertensive effect of ACE inhibitors.

Pharmacological Class:

Bradykinin B2 receptor antagonist.

Adverse Reactions:

Inj site reactions, pyrexia, transaminase increase, dizziness, rash.

Generic Availability:

NO

How Supplied:

Single-use prefilled syringe (3mL)—1, 3

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