Hirsutism affects androgen-dependent areas of a woman’s body and only involves terminal hair – the thick, pigmented hair found on the scalp, beard, armpit and pubic areas.
Although the terms hirsutism and hypertrichosis are often used interchangeably, hypertrichosis involves excess hair growth in areas of the body that are not androgen dependent. Notably, hypertrichosis involves excess lanugo and vellus hair, which are fine, downy and non-pigmented and resemble peach fuzz.
Most forms of hirsutism are idiopathic and occur in women with normal levels of male hormones who do not have menstrual abnormalities — especially after menopause and among those with dark hair. Idiopathic hirsutism is believed to be caused by hair follicles that are overly sensitive to male hormones.
Hirsutism may also be a manifestation of a more serious underlying malignancy, such as ovarian or adrenal neoplasms. Any condition that increases blood levels of testosterone, male sex hormone or androgen can cause hirsutism including: polycystic ovary syndrome, congenital adrenal hyperplasia, and androgen-producing tumors of the ovary or adrenal gland.
Certain medications, especially those that affect androgen levels, can induce hirsutism. These include dehydroepiandrosterone sulfate (DHEA-S), testosterone, danazol, and anabolic steroids. Other drugs associated with hirsutism include phenytoin, minoxidil, diazoxide, cyclosporine, streptomycin, psoralen, penicillamine, high-dose corticosteroids, metyrapone, phenothiazines, acetazolamide, and hexachlorobenzene.
- Whole Genome Sequencing Reveals that 12% of Childhood Cancer Survivors Have Mutations in Genes that Increase Cancer Risk
- Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab
- Novel Test For Multiple Myeloma Uses Microchip, Conventional Blood Sample
- Health Care Expansion Tied to Increased Rates of Surgical Treatment of Thyroid Cancer
- Including a PI3-Kinase Inhibitor with an PARP Inhibitor Improves Tumor Shrinkage in Patients with Resistant Ovarian Cancer
- Exercise, Psychological Interventions Better for Cancer Fatigue Than Medications
- ASCO Issues Global Guidance for HPV Vaccination for Cervical Cancer Prevention
- Discharge Events Improved With Standardized Inpatient Palliative Care Consultation
- Little Opposition to Early Palliative Care for Symptom Management in Pediatric Oncology
- Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors
- Family History Does Not Exclude Active Surveillance as Treatment Option for Prostate Cancer
- Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors
- Hormone Refractory Prostate Cancer Responds to Abiraterone Acetate in Some Cases
- Shifts in Cancer Burden for People With HIV Projected
- Tissue Biobank Procurement Consent Should Include Discussion of Confidentiality Risks
Sign Up for Free e-newsletters
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|