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ERAXIS
Fungal infections
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Drug Name:

ERAXIS Rx

Generic Name and Formulations:
Anidulafungin 50mg/vial, 100mg/vial; pwd for IV infusion after reconstitution and dilution; preservative-free; contains fructose and mannitol.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for ERAXIS:

Candidemia. Esophageal candidiasis. Other Candida infections (intra-abdominal abscess, peritonitis).

Adult:

Give by IV infusion; max rate 1.1mg/minute. Candidiasis, intra-abdominal abscess, peritonitis: 200mg on day 1, then 100mg/day for at least 14 days after last positive culture. Esophageal candidiasis: 100mg on day 1, then 50mg/day for at least 14 days and at least 7 days after symptom resolution.

Children:

≤16yrs: not established.

Warnings/Precautions:

Follow-up if hepatic dysfunction develops. Discontinue and treat appropriately if anaphylactic reactions occur. Pregnancy: avoid. Nursing mothers.

Pharmacological Class:

Glucan synthesis inhibitor (echinocandin).

Adverse Reactions:

Hypokalemia, GI upset, pyrexia, insomnia, anemia, headache, dyspepsia; hepatic effects, infusion reactions, anaphylactic reactions.

Elimination:

Fecal, renal (minor).

Generic Availability:

NO

How Supplied:

Vial—1

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