Epigenetics

Combining epigenetic therapies with immunotherapies may improve outcomes for cancer patients

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Recent data suggest that epigenetic therapies are likely to provide additional clinical benefit to patients with cancer when rationally combined with immunotherapeutic drugs.

New drug target and companion prognostic test for hormone therapy-resistant breast cancer

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Researchers have identified the signaling pathway that is overactivated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors, or fulvestrant.

Epigenetic changes have a key role in chemotherapy resistance in bladder cancer

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A new study of neoadjuvant cisplatin-based chemotherapy showed that epigenetic changes are potential key drivers in the development of chemotherapy resistance in bladder cancer.

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