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Ephedrine Sulfate Injection
Anesthetics
Asthma/COPD
Myasthenia gravis
Sleep-wake disorders
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Drug Name:

Ephedrine Sulfate Injection Rx

Generic Name and Formulations:
Ephedrine sulfate 50mg/mL; soln for IM, IV, or SC inj.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Ephedrine Sulfate Injection:

As a pressor agent, particularly during spinal anesthesia when hypotension frequently occurs.

Adult:

25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.

Children:

0.5mg/kg by SC or IM every 4–6 hours.

Warnings/Precautions:

Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.

Pharmacological Class:

Sympathomimetic.

Adverse Reactions:

Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.

How Supplied:

Contact supplier.

Indications for Ephedrine Sulfate Injection:

Treatment of allergic disorders, such as bronchial asthma.

Adult:

25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.

Children:

0.5mg/kg by SC or IM every 4–6 hours.

Warnings/Precautions:

Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.

Pharmacological Class:

Sympathomimetic.

Adverse Reactions:

Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.

How Supplied:

Contact supplier.

Indications for Ephedrine Sulfate Injection:

Myasthenia gravis.

Adult:

25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.

Children:

0.5mg/kg by SC or IM every 4–6 hours.

Warnings/Precautions:

Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.

Pharmacological Class:

Sympathomimetic.

Adverse Reactions:

Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.

How Supplied:

Contact supplier.

Indications for Ephedrine Sulfate Injection:

As a CNS stimulant in narcolepsy and depressive states.

Adult:

25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.

Children:

0.5mg/kg by SC or IM every 4–6 hours.

Warnings/Precautions:

Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.

Pharmacological Class:

Sympathomimetic.

Adverse Reactions:

Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.

How Supplied:

Contact supplier.

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