Elderly

How to get smarter on pills for seniors

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A recent study has determined that a more comprehensive medication assessment and monitoring plan is needed to improve proper drug self-administration for the elderly population.

Colorectal cancer resection mortality still high for elderly

Colorectal cancer resection mortality still high for elderly

Despite an overall improved mortality seen during the past 10 years, advancing age is associated with higher morbidity and mortality in colorectal cancer resection.

Faster cognitive decline lowers cancer mortality risk

Faster cognitive decline lowers cancer mortality risk

Elderly with faster cognitive decline were found to have lower risk of cancer mortality, according to research.

Racial disparities seen in functional disability of breast cancer

Racial disparities seen in functional disability of breast cancer

More likely among African-American women with newly diagnosed non-metastatic breast cancer

Cancer in the very elderly: Three programs designed especially for frail patients

Cancer in the very elderly: Three programs designed especially for frail patients

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These programs are designed to address the unique challenges of providing cancer care to patients older than 65 years.

Elderly can benefit from 
palliative radiotherapy

Elderly can benefit from 
palliative radiotherapy

Researchers recommend that palliative radiotherapy be considered for painful bone metastases in the elderly, after patients demonstrated a meaningful response to this treatment with no QoL reduction.

Trastuzumab raises heart risk in older women with breast cancer

Heart failure is relatively common in older women undergoing breast cancer treatment, but trastuzumab therapy appears to raise the risk even more.

Withdrawn leukemia drug has good results in UK study

Gemtuzumab ozogamicin, discontinued here in 2010, reduced relapse risk and improved survival in Welsh patients with acute myeloid leukemia.

Radiotherapy after prostatectomy has long-term benefits

Administering radiotherapy after prostatectomy helped nearly two-thirds of users in a recent study remain free of prostate cancer after 10 years.

Older breast cancer patients have more complications with brachytherapy

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The breast cancer treatment brachytherapy, heralded for its low complication rates, actually results in more complications than whole-breast radiation 1 year after treatment.

All-cause mortality is reduced in elderly female cancer survivors who adhere to lifestyle guidelines

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Survival after cancer diagnosis in elderly female cancer survivors is improved by achieving and maintaining a healthy body weight, staying physically active, and maintaining a healthy diet.

HF/CM risks in breast chemotherapy

HF/CM risks in breast chemotherapy

Earlier study findings that anthracycline- or trastuzumab-based treatment for breast cancer raises the risk for heart failure and cardiomyopathy can be extended to a more general population of women.

Aspirin helps in some cancers

Aspirin helps in some cancers

Differences in the impact of aspirin in various forms of cancer are highlighted in two studies recently published in the oncology literature.

New colonoscopy schedule mirrors prior advice

Two of three main recommendations for colonoscopy surveillance are now supported by stronger evidence than they were in 2006.

Intracranial tumors can be resected safely in elderly

Intracranial tumors can be resected safely in elderly

Short-term outcomes no worse with advanced age after craniotomy for malignant brain tumors.

Older age marker may be a more appropriate predictor of prognosis in papillary thyroid cancer

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Younger age at diagnosis is no longer a useful predictor of negative outcomes in the staging of patients with papillary thyroid cancer. Prognosis for survival in thyroid cancer does not drop until age 65 to 74 years, and those patients still have 92.0% survival.

Fit elderly patients with NSCLC should be considered for therapy

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Fit elderly patients with non-small cell lung cancer (NSCLC) should be considered for salvage targeted therapy. Many physicians use age to decide what therapy to give their patients, since validated biomarkers to direct treatment decisions are lacking.

Patients with colorectal or bladder cancer may benefit from advanced surgical approaches

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Robotic-assisted operations and minimally invasive surgical procedures may extend survival and improve recovery in these patients compared with conventional open operations, according to recent studies presented at the 2012 Annual Clinical Congress of the American College of Surgeons.

Direct-mail FOBT kits bridge colorectal screening gap

The mailing of fecal occult blood test (FOBT) kits boosted colorectal cancer screening rates in a low-income, racially diverse patient population.

Disparities in surgical management of thyroid cancer

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ATA guidelines for well-differentiated thyroid cancer recommend therapeutic neck dissection when the disease is clinically involved or metastatic and prophylactic central neck dissection when tumors are advanced. Nonetheless, though these established guidelines are in place, the surgical management of cervical nodes varies greatly.

No Benefit Seen for Adjuvant Oxaliplatin in Stage II Colon CA

No Benefit Seen for Adjuvant Oxaliplatin in Stage II Colon CA

Subgroup analysis shows no survival benefit for adjuvant oxaliplatin in the elderly or those with stage II disease.

Only a few gene mutations important in leukemia

Most of the hundreds of mutations found in acute myeloid leukemia (AML) genomes occur randomly as part of the aging process, unrelated to cancer.

Radiation Prevents Mastectomy Post-Conservative Op in Elderly

Radiation Prevents Mastectomy Post-Conservative Op in Elderly

RT in this population results in greater likelihood of breast conservation.

Guidelines: screen for lung cancer with low-dose CT

The American Association for Thoracic Surgery wants annual lung cancer screening for 55-to-79-year-olds with a 30 pack-year history of smoking.

Laxative-free virtual colonoscopy can detect large polyps

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CT colonography can accurately detect adenomas 10 mm or larger in patients who did not undergo laxative-induced bowel cleansing before the procedure.

Younger CRC patients have worse presentation but comparable survival

Colorectal cancer patients under 50 had worse histological characteristics and earlier metastasis but survival equal to or better than older patients.

Diagnosis delayed for certain cancers and certain patients

A large UK study found a wide variation between cancer types in patients who had visited their general practitioner 3 or more times before cancer diagnosis.

Chemoradiotherapy prolongs life for older patients with lung cancer

Survival improved for elderly patients with non-small cell lung cancer who had combined chemotherapy and radiotherapy rather than radiotherapy alone.

CT lung screening useful for some smokers, but drawbacks remain

Annual lung cancer screening with low-dose computed tomography may benefit some smokers, but uncertainty exists as to the harms of screening.

Virtual colonoscopy is an accurate screen in seniors

Virtual colonoscopy is an accurate screen in seniors

CT colonography accurately detects cancer and precancerous polyps in persons aged 65 years and older.

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