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EDECRIN
Edema
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Drug Name:

EDECRIN Rx

Generic Name and Formulations:
Ethacrynic acid 25mg; scored tabs.

Company:
Valeant Pharmaceuticals, Inc

Therapeutic Use:

Indications for EDECRIN:

Treatment of edema when greater diuretic potential is required.

Adult:

Initially 50–100mg daily; adjust in 25–50mg increments. Usual maintenance: 50–200mg daily or intermittently.

Children:

See Contraindications. Initially 25mg; adjust gradually in 25mg increments (see literature).

Contraindications:

Anuria. Infants. If severe, watery diarrhea occurs, discontinue use and do not restart.

Warnings/Precautions:

Renal impairment. Hepatic cirrhosis. Monitor weight, renal function, electrolytes, CO2, BUN. Potassium supplementation may be needed. Elderly. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Digitalis, lithium toxicity. May alter excretion of lithium. Potentiates warfarin. Antagonized by NSAIDs. Orthostatic hypotension with antihypertensives. Ototoxicity with aminoglycosides, other ototoxic agents. May alter glucose tolerance tests.

Pharmacological Class:

Diuretic (loop).

Adverse Reactions:

GI upset, anorexia, malaise, abdominal pain, dysphagia, ototoxicity, vertigo, headache, rash, electrolyte imbalance, hyperuricemia, gout, hyperglycemia; rare: agranulocytosis, severe neutropenia, thrombocytopenia.

How Supplied:

Tabs—100

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