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DONNATAL ELIXIR
Hyperacidity, GERD, and ulcers
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Drug Name:

DONNATAL ELIXIR Rx

Generic Name and Formulations:
Phenobarbital 16.2mg, hyoscyamine sulfate 0.1037mg, atropine sulfate 0.0194mg, scopolamine HBr 0.0065mg; per 5mL; contains alcohol; grape flavor.

Company:
Concordia Pharmaceuticals Inc.

Therapeutic Use:

Indications for DONNATAL ELIXIR:

Adjunct in irritable bowel syndrome, enterocolitis, duodenal ulcer.

Adult:

5–10mL 3–4 times daily.

Children:

<10lb (4.5kg): not recommended. 10lb (4.5kg): Initially 0.5mL every 4hrs or 0.75mL every 6hrs. 20lb (9.1kg): 1mL every 4hrs or 1.5mL every 6hrs. 30lb (13.6kg): 1.5mL every 4hrs or 2mL every 6hrs. 50lb (22.7kg): 2.5mL every 4hrs or 3.75mL every 6hrs. 75lb (34kg): 3.75mL every 4hrs or 5mL every 6hrs. 100 lb (45.4kg): 5mL every 4hrs or 7.5mL every 6hrs.

Contraindications:

Glaucoma. Porphyria. Unstable cardiovascular status. GI or GU obstruction. Paralytic ileus or intestinal atony. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis. Hiatal hernia. History of paradoxical reactions to phenobarbital.

Warnings/Precautions:

Renal or hepatic impairment. Autonomic neuropathy. Cardiovascular disease. Hypertension. Hyperthyroidism. Drug abusers. High environmental temperature. Gastric ulcer. Diarrhea. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Potentiated CNS depression with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics, narcotics, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics. May antagonize anticoagulants, CYP450 substrates.

See Also:

DONNATAL TABLETS

Pharmacological Class:

Barbiturate + anticholinergics.

Adverse Reactions:

Drowsiness, anticholinergic effects, paradoxical excitement.

How Supplied:

Tabs—100, 1000; Elixir—4oz, pt

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