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Diphenhydramine Injection
Allergies
Nausea
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Drug Name:

Diphenhydramine Injection Rx

Generic Name and Formulations:
Diphenhydramine HCl 50mg/mL; for IV or IM inj.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Diphenhydramine Injection:

Allergic disorders where oral form is impractical or contraindicated. Adjunct in anaphylaxis. Allergic reactions to blood or plasma.

Adult:

10–50mg IV or deep IM; max 400mg/day.

Children:

Neonates: not recommended. Others: 5mg/kg per day in 4 divided doses IV or deep IM; max 300mg daily in 4 divided doses.

Contraindications:

Neonates. Premature infants. Acute asthma. Concomitant diphenhydramine products (including topicals).

Warnings/Precautions:

Asthma and lower respiratory disorders. Glaucoma. Hyperthyroidism. Hypertension. Cardiovascular disease. GI or urinary obstruction. Sodium-restricted diet. Children. Pregnancy (Cat.B in 3rd trimester): not recommended. Nursing mothers.

Interactions:

Potentiates CNS depression with alcohol, other CNS depressants. Potentiates anticholinergic effects with MAOIs.

See Also:

BENADRYL ALLERGY

BENADRYL ALLERGY LIQUID

Pharmacological Class:

Antihistamine.

Adverse Reactions:

Drowsiness, dizziness, anticholinergic effects, excitability in children.

How Supplied:

Caps—24, 48; Tabs—24, 48, 100; Dye-free softgels—24; Allergy Liq—4oz, 8oz; Dye-free Liq—4oz; Inj—contact supplier

Indications for Diphenhydramine Injection:

Motion sickness.

Adult:

10–50mg IV or deep IM; max 400mg/day.

Children:

Neonates: not recommended. Others: 5mg/kg per day in 4 divided doses IV or deep IM; max 300mg daily in 4 divided doses.

Contraindications:

Neonates. Premature infants. Nursing mothers.

Warnings/Precautions:

Asthma. Lower respiratory disorders. Glaucoma. Hyperthyroidism. Hypertension. Cardiovascular disease. GI or urinary obstruction. Children. Pregnancy (Cat.B).

Interactions:

Potentiates CNS depression with alcohol, other CNS depressants. Potentiates anticholinergic effects with MAOIs.

Pharmacological Class:

Antihistamine.

Adverse Reactions:

Drowsiness, dizziness, anticholinergic effects, gastritis, paradoxical excitement, blood dyscrasias, hypotension.

How Supplied:

Contact supplier.

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