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DIBENZYLINE
Hypertension
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Drug Name:

DIBENZYLINE Rx

Generic Name and Formulations:
Phenoxybenzamine HCl 10mg; caps.

Company:
WellSpring Pharmaceuticals, Corp.

Therapeutic Use:

Indications for DIBENZYLINE:

Treatment of pheochromocytoma, to control episodes of hypertension and sweating. May use concomitant β-blocker if tachycardia is excessive.

Adult:

Individualize. Initially 10mg twice daily. Increase dose every other day, usually to 20–40mg 2 or 3 times daily, until optimal dose obtained. Observe patients after each increase before instituting another increase.

Children:

Not recommended.

Contraindications:

Conditions where a fall in BP may be undesirable.

Warnings/Precautions:

Cerebral or coronary arteriosclerosis. Renal damage. May aggravate respiratory infections. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Concomitant drugs that stimulate both alpha- and beta-adrenergic receptors (eg, epinephrine) may produce exaggerated hypotensive response and tachycardia. Blocks hyperthermia production by levarterenol. Blocks hypothermia production by reserpine.

Pharmacological Class:

Alpha adrenergic blocker.

Adverse Reactions:

Postural hypotension, tachycardia, inhibition of ejaculation, nasal congestion, miosis, GI upset, drowsiness, fatigue. May be carcinogenic (w. long-term use: not recommended).

How Supplied:

Caps—100

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