Diagnosis

More Than Half of Melanomas Are Self-Detected, Especially by Women

More Than Half of Melanomas Are Self-Detected, Especially by Women

More melanomas are self-detected by women; men tend to have more melanomas in less visible locations.

Patient Navigation Reduces Delays in Diagnostic Resolution

Patient Navigation Reduces Delays in Diagnostic Resolution

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Patient navigation reduces delays in diagnostic resolution among patients with a Charlson Comorbidity Index greater than 1 with abnormal findings

Epigenetic Profiling Improves Identification of Primary Tumor in CUP

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DNA methylation profiling identified the primary cancer in cases of cancer of unknown primary, informing tumor-type specific treatment that improved overall survival in these patients.

Lung Cancer Signature Detected Via Breath Test Improves Early Diagnosis

Lung Cancer Signature Detected Via Breath Test Improves Early Diagnosis

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Breath analysis offers an option for both primary screening and postsurgery monitoring of patients with lung cancer. Exhaled breath has certain carbonyl VOCs that indicate the presence of lung cancer in a process researchers hope will receive FDA approval.

Most Patients Experience Posttraumatic Stress Disorder After a Breast Cancer Diagnosis

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Symptoms of posttraumatic stress disorder (PTSD) develop in a majority of patients with breast cancer, and these symptoms persist for at least a year for most.

Survival and Time to Surgery and Chemotherapy for Patients With Breast Cancer

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More than 3 months from surgery to chemotherapy and increasing delays from diagnosis to surgery in patients with breast cancer are associated with increased risk of death from the disease.

Portal Vein Blood Leads to Earlier, More Accurate Pancreatic Cancer Diagnosis

Portal Vein Blood Leads to Earlier, More Accurate Pancreatic Cancer Diagnosis

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Blood samples collected from the portal vein can tell physicians far more about a patient's pancreatic cancer than peripheral blood collected from a more easily accessed vein in the arm.

Personalized Drug Screen Aids Treatment Selection for Patients with Multiple Myeloma

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A personalized testing method may quickly and more accurately predict the effectiveness of a treatment for multiple myeloma in individual patients. The process may also aid patients with leukemia or lymphoma.

Affordable Care Act (ACA) Impacts Stage at Diagnosis and Fertility-Sparing Treatment in Young Women With Cervical Cancer

Affordable Care Act (ACA) Impacts Stage at Diagnosis and Fertility-Sparing Treatment in Young Women With Cervical Cancer

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Both the stage of cervical cancer at diagnosis and the receipt of fertility-sparing treatment among young women age 21 to 25 years, but not among women age 26 to 34 years, is associated with the Affordable Care Act Dependent Coverage Expansion provision.

New Blood Test Improves Screening for Prostate Cancer

New Blood Test Improves Screening for Prostate Cancer

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A new test is better at detecting aggressive prostate cancer than measuring PSA levels. The new test discovers aggressive cancer earlier and reduces the number of false positive tests and unnecessary biopsies.

Blood Sample Offers a New Way of Detecting Cancer

Blood Sample Offers a New Way of Detecting Cancer

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RNA test of blood platelets can detect, classify, and pinpoint the location of cancer by analyzing a sample equivalent to 1 drop of blood. Using this new method, researchers were able to identify cancer with 96% accuracy.

Scientists Uncover Genetic Landscape of Fibroepithelial Breast Tumors

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The genetic landscape of fibroepithelial tumors has been uncovered. The culprit genes behind the formation and progression of these tumors were identified, potentially improving the diagnostic accuracy of breast cancer and enhancing clinical intervention for patients with this tumor type.

Colorectal Cancer Tumors Differ in Younger vs Older Patients

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Researchers report that CRC tumors in younger persons may be molecularly distinct from those of older persons, and that these differences are related to epigenetics of the tumors in younger patients.

DNA shed from head and neck tumors detected in blood and saliva

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A new proof of principle study seems to validate the usefulness of DNA testing to detect cancers in the oral cavity.

Injury to the big toe leads to an unexpected lymphoma

Injury to the big toe leads to an unexpected lymphoma

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A seemingly innocuous injury to the foot produces a persistent lesion. Punch biopsy reveals an unusual diagnosis.

Rate of new prostate cancer diagnoses drops

Rate of new prostate cancer diagnoses drops

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New diagnoses of prostate cancer have declined in the U.S. following the 2011 USPSTF draft recommendation regarding the use of prostate-specific antigen (PSA)-based screenings.

Distinct triple-positive subtypes identified in breast cancer

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CHICAGO, IL—Functional subtyping with a multigene classifier resulted in 1 in 5 tumors being reclassified compared with conventional immunohistochemistry/fluorescent in situ hybridization (IHC/FISH) analysis. This study was presented at the 2015 American Society for Clinical Oncology (ASCO) Annual Meeting.

MRI detection of sugar molecules on cells may enable distinction of cancer vs noncancerous cells

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Study data suggests that magnetic resonance imaging (MRI) could one day make biopsies more effective, or even replace them altogether, via noninvasive detection of telltale sugar molecules shed by the outer membranes of cancerous cells.

Study examined diagnostic accuracy of breast biopsy interpretations

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A comparison of the diagnostic interpretation of breast biopsy slides by pathologists and that of an expert consensus panel yielded an overall agreement of 75%.

Prior diagnosis of MGUS improves survival in patients with multiple myeloma

Prior diagnosis of MGUS improves survival in patients with multiple myeloma

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Patients with multiple myeloma seem to have improves survival if they are found to have monoclonal gammopathy of undetermined significance (MGUS) first.

ASCO: High-risk prostate cancer diagnosis up since new PSA recommendations

ASCO: High-risk prostate cancer diagnosis up since new PSA recommendations

Researchers report 3 percent annual rise in intermediate- and high-risk cases

Cancer diagnosis impacts patient adherence to diabetes meds

Cancer diagnosis impacts patient adherence to diabetes meds

When diagnosed with cancer, individuals with diabetes are less likely to take their diabetes medication, especially in cases of a poor cancer prognosis.

Breast cancer is more accurately diagnosed after PET/CT imaging in younger patients

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A change in diagnosis resulted from PET/CT imaging of patients who were younger than 40 years with an initial diagnosis of stage I-III breast cancer, according to a retrospective analysis.

Molecular panel increases likelihood that initial surgery for thyroid cancer is corrective

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Routine use of a molecular testing panel greatly decreased the need for an initial lobectomy to confirm diagnosis in patients with thyroid nodules and cancer, reported researchers. The test improved the chances of patients undergoing the correct initial surgery by 30%.

Pain and itch may indicate skin cancer

Pain and itch may indicate skin cancer

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Asking patients if a suspicious skin lesion is painful or itchy may help doctors decide whether the spot is likely to be cancerous, according to a new study.

Painful, Itchy Patches Could Be Sign of Non-Melanoma Skin Cancer

Painful, Itchy Patches Could Be Sign of Non-Melanoma Skin Cancer

Suspicious looking lesions that are painful or itchy should raise concerns for non-melanoma skin cancers, according to research from Temple University School of Medicine.

Obtaining 16 cores is better than obtaining 12 cores for prostate cancer detection

Obtaining 16 cores is better than obtaining 12 cores for prostate cancer detection

A research team from Japan found that 16-core biopsy has a slightly higher detection rate than 12-core biopsy.

Building a great support system for patients with breast cancer

Building a great support system for patients with breast cancer

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The driving forces in the evolution of health care are the aging US population, an increasing cultural awareness of health and cancer, and recognition of patients as consumers.

Patients with breast cancer underuse needle biopsy

Patients with breast cancer underuse needle biopsy

Needle biopsy appears to be underused in patients with breast cancer, according to a study published online June 9 in the Journal of Clinical Oncology.

Blood-based biomarker panel may enable pancreatic cancer diagnosis at an early stage

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A panel of four blood biomarkers successfully distinguished patients with pancreatic cancer from those who were healthy, had chronic pancreatitis, or had pancreatic cysts approximately 90% of the time.

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